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Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to both exo and endonucleases.

التفاصيل البيبلوغرافية
العنوان:	Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to both exo and endonucleases.
المؤلفون:	Pradeepkumar, Pushpangadan I, Amirkhanov, Nariman V, Chattopadhyaya, Jyoti
المصدر:	Org Biomol Chem. 1(1):81-92
مصطلحات موضوعية:	Base Sequence, Cytidine/chemistry, Deoxyribonuclease I/chemistry, Dose-Response Relationship, Drug, Electrophoresis, Polyacrylamide Gel, Endonucleases/pharmacology, Ethers, Cyclic/chemistry, Exonucleases/chemistry/pharmacology, Humans, Kinetics, Models, Chemical, Molecular Sequence Data, Nucleic Acid Conformation, Nucleotides/pharmacology, Oligonucleotides, Antisense/pharmacology, Protein Binding, RNA/chemistry, Research Support, Non-U.S. Gov't, Ribonuclease H, Calf Thymus/chemistry, Temperature
وصف الملف:	print
الوصول الحر:	https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-73474Test http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&cmd=Retrieve&list_uids=12929393&dopt=CitationTest
قاعدة البيانات:	SwePub

الوصف
تدمد:	14770520