التفاصيل البيبلوغرافية
| العنوان: |
CAPSULE PHOTOTHERAPY |
| Document Number: |
20130013031 |
| تاريخ النشر: |
January 10, 2013 |
| Appl. No: |
13/634555 |
| Application Filed: |
March 17, 2011 |
| مستخلص: |
The present invention provides a swallowable capsule suitable for providing phototherapy to a region of a patient's gastrointestinal (GI) tract, the capsule comprising one or more light sources emitting in the visible and/or NIR ranges and optical elements for shaping the light beam produced by said light sources, such that said light source(s) and said optical elements are capable of delivering an effective therapeutic dose to a target site within the GI tract. The present invention further provides a method for intraluminal phototherapy of the gastrointestinal tract using a swallowable capsule as described hereinabove. |
| Inventors: |
Ben-Yehuda, Sharon (Rechovot, IL); Ben-Yehuda, Ram (Rechovot, IL) |
| Assignees: |
PHOTOPILL MEDICAL LTD. (Rechovot, IL) |
| Claim: |
1. A swallowable capsule for providing phototherapy to a region of a patient's gastrointestinal (GI) tract, the capsule comprising: one or more light sources emitting in the visible and/or NIR ranges; and optical elements for shaping the light beam produced by said light sources, such that said light source(s) and said optical elements are capable of delivering an effective therapeutic dose to a target site within the GI tract. |
| Claim: |
2. The swallowable capsule according to claim 1, wherein the light radiation produced by the light source(s) is transmitted out of said capsule in a direction that is essentially perpendicular to the longitudinal axis thereof, and wherein said transmitted light is in the form of an essentially circular narrow band of light surrounding said capsule. |
| Claim: |
3. The swallowable capsule according to claim 1, wherein the light sources emit light centered at one or more wavelengths in the ranges selected from the group consisting of 400-480 nm, 610-720 nm and 800-950 nm. |
| Claim: |
4. The swallowable capsule according to claim 3, wherein the light sources emit light centered at one or more wavelengths selected from the group consisting of 440 nm, 660 nm and 850 nm. |
| Claim: |
5. The swallowable capsule according to claim 1, further comprising means for determining the direction, speed of movement and location of said capsule. |
| Claim: |
6. The swallowable capsule according to claim 5, wherein the means for determining the direction, speed of movement and location of said capsule is selected from the group consisting of an accelerometer and an optical motion-sensing system. |
| Claim: |
7. The swallowable capsule according to claim 1, wherein said capsule further comprises one or more microprocessors and associated circuitry. |
| Claim: |
8. The swallowable capsule according to claim 1 wherein said capsule further comprises a timer. |
| Claim: |
9. The swallowable capsule according to claim 1, wherein said capsule further comprises a switch selected from the group consisting of a magnetic switch and a mechanical switch, and wherein said switch is capable of turning on one or more elements defined in the preceding claims selected from the group consisting of a timer, an accelerometer and an optical motion-sensing system. |
| Claim: |
10. The swallowable capsule according to claim 9, wherein the switch is capable of being activated upon removal of said capsule from a package. |
| Claim: |
11. The swallowable capsule according to claim 9, wherein the switch is a mechanical switch which is capable of being activated by means of squeezing the capsule. |
| Claim: |
12. The swallowable capsule according to claim 1, wherein said capsule further comprises means for detecting changes in the ambient environment of the capsule. |
| Claim: |
13. The swallowable capsule according to claim 12, wherein the means for detecting changes in the ambient environment of the capsule comprise a pH sensor. |
| Claim: |
14. A method for intraluminal phototherapy of the gastrointestinal tract in a patient in need of such treatment, wherein said method comprises the steps of: a) providing a swallowable capsule according to claim 1; and b) oral administration of said capsule to said patient. |
| Claim: |
15. The method according to claim 14, wherein the oral administration to the patient is by way of self-administration. |
| Claim: |
16. The method according to claim 14, wherein said method is used to treat inflammatory bowel disease. |
| Claim: |
17. The method according to claim 16, wherein the inflammatory bowel disease is selected from the group consisting of Crohn's disease, ulcerative colitis and indeterminate colitis. |
| Claim: |
18. The method according to claim 14, wherein said method is used to promote healing of the intestinal mucosa and submucosal tissues. |
| Claim: |
19. The method according to claim 14, wherein said method is used to treat lesions in the small intestine. |
| Claim: |
20. The method according to claim 14, wherein said method is used to treat mucosa in the small intestine. |
| Current U.S. Class: |
607/92 |
| Current International Class: |
61 |
| رقم الانضمام: |
edspap.20130013031 |
| قاعدة البيانات: |
USPTO Patent Applications |
