دورية أكاديمية
Assessment of patient-led or physician-driven continuous glucose monitoring in patients with poorly controlled type 1 diabetes using basal-bolus insulin regimens: a 1-year multicenter study.
| العنوان: | Assessment of patient-led or physician-driven continuous glucose monitoring in patients with poorly controlled type 1 diabetes using basal-bolus insulin regimens: a 1-year multicenter study. |
|---|---|
| المؤلفون: | Riveline, Jean-Pierre, Schaepelynck, Pauline, Chaillous, Lucy, Renard, Eric, Sola-Gazagnes, Agnes, Penfornis, Alfred, Tubiana-Rufi, Nadia, Sulmont, Veronique, Catargi, Bogdan, Lukas, Celine, Radermecker, Régis, Thivolet, Charles, Moreau, Francois, Benhamou, Pierre-Yves, Guerci, Bruno, Leguerrier, Anne-Marie, Millot, Luc, Sachon, Claude, Charpentier, Guillaume, Hanaire, Helene |
| المصدر: | Diabetes Care, 35 (5), 965-71 (2012) |
| بيانات النشر: | American Diabetes Association, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adolescent, Adult, Blood Glucose/analysis, Blood Glucose Self-Monitoring/methods, Child, Diabetes Mellitus, Type 1/blood/drug therapy, Female, Hemoglobin A, Glycosylated/metabolism, Humans, Hypoglycemic Agents/therapeutic use, Insulin/therapeutic use, Male, Middle Aged, Physicians, Young Adult, Human health sciences, Endocrinology, metabolism & nutrition, Sciences de la santé humaine, Endocrinologie, métabolisme & nutrition |
| الوصف: | OBJECTIVE: The benefits of real-time continuous glucose monitoring (CGM) have been demonstrated in patients with type 1 diabetes. Our aim was to compare the effect of two modes of use of CGM, patient led or physician driven, for 1 year in subjects with poorly controlled type 1 diabetes. RESEARCH DESIGN AND METHODS: Patients with type 1 diabetes aged 8-60 years with HbA(1c) >/= 8% were randomly assigned to three groups (1:1:1). Outcomes for glucose control were assessed at 1 year for two modes of CGM (group 1: patient led; group 2: physician driven) versus conventional self-monitoring of blood glucose (group 3: control). RESULTS: A total of 257 subjects with type 1 diabetes underwent screening. Of these, 197 were randomized, with 178 patients completing the study (age: 36 +/- 14 years; HbA(1c): 8.9 +/- 0.9%). HbA(1c) improved similarly in both CGM groups and was reduced compared with the control group (group 1 vs. group 3: -0.52%, P = 0.0006; group 2 vs. group 3: -0.47%, P = 0.0008; groups 1 + 2 vs. group 3: -0.50%, P < 0.0001). The incidence of hypoglycemia was similar in the three groups. Patient SF-36 questionnaire physical health score improved in both experimental CGM groups (P = 0.004). Sensor consumption was 34% lower in group 2 than in group 1 (median [Q1-Q3] consumption: group 1: 3.42/month [2.20-3.91] vs. group 2: 2.25/month [1.27-2.99], P = 0.001). CONCLUSIONS: Both patient-led and physician-driven CGM provide similar long-term improvement in glucose control in patients with poorly controlled type 1 diabetes, but the physician-driven CGM mode used fewer sensors. |
| نوع الوثيقة: | journal article http://purl.org/coar/resource_type/c_6501Test article |
| اللغة: | English |
| العلاقة: | urn:issn:0149-5992; urn:issn:1935-5548 |
| DOI: | 10.2337/dc11-2021 |
| الوصول الحر: | https://orbi.uliege.be/handle/2268/196142Test |
| حقوق: | open access http://purl.org/coar/access_right/c_abf2Test info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsorb.196142 |
| قاعدة البيانات: | ORBi |
| DOI: | 10.2337/dc11-2021 |
|---|