مورد إلكتروني
ERP evidence of semantic processing in children with ASD.
| العنوان: | ERP evidence of semantic processing in children with ASD. |
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| المؤلفون: | DiStefano, Charlotte |
| بيانات النشر: | eScholarship, University of California 2019-04-01 |
| تفاصيل مُضافة: | DiStefano, Charlotte Senturk, Damla Jeste, Shafali Spurling |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | 25% of children with autism spectrum disorder (ASD) remain minimally verbal (MV), despite intervention. Electroencephalography can reveal neural mechanisms underlying language impairment in ASD, potentially improving our ability to predict language outcomes and target interventions. Verbal (V) and MV children with ASD, along with an age-matched typically developing (TD) group participated in a semantic congruence ERP paradigm, during which pictures were displayed followed by the expected or unexpected word. An N400 effect was evident in all groups, with a shorter latency in the TD group. A late negative component (LNC) also differentiated conditions, with a group by condition by region interaction. Post hoc analyses revealed that the LNC was present across multiple regions in the TD group, in the mid-frontal region in MVASD, and not present in the VASD group. Cluster analysis identified subgroups within the ASD participants. Two subgroups showed markedly atypical patterns of processing, one with reversed but robust differentiation of conditions, and the other with initially reversed followed by typical differentiation. Findings indicate that children with ASD, including those with minimal language, showed EEG evidence of semantic processing, but it was characterized by delayed speed of processing and limited integration with mental representations. |
| مصطلحات الفهرس: | Humans, Electroencephalography, Semantics, Child, Female, Male, Autism Spectrum Disorder, ASD, Autism, EEG, ERP, Language, Clinical Research, Intellectual and Developmental Disabilities (IDD), Pediatric, Neurosciences, Brain Disorders, Mental Health, 2.1 Biological and endogenous factors, 2.3 Psychological, social and economic factors, Aetiology, 1.1 Normal biological development and functioning, Underpinning research, Mental health, Clinical Sciences, Cognitive Sciences, publication |
| URL: | |
| الإتاحة: | Open access content. Open access content public |
| ملاحظة: | application/pdf |
| أرقام أخرى: | CDLER oai:escholarship.org:ark:/13030/qt8d84c1b4 qt8d84c1b4 https://escholarship.org/uc/item/8d84c1b4Test https://escholarship.orgTest/ 1367409667 |
| المصدر المساهم: | UC MASS DIGITIZATION From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1367409667 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |