التفاصيل البيبلوغرافية
| العنوان: |
Pregnancy Prolongation after Eculizumab Use in Early-Onset Preeclampsia. |
| بيانات النشر: |
Lippincott Williams and Wilkins (E-mail: agents@lww.com) United Kingdom 2020-03-05 |
| تفاصيل مُضافة: |
Lazarus B.
Palmer, Kirsten R.
Rolnik D.L.
Lu A.B. |
| نوع الوثيقة: |
Electronic Resource |
| مستخلص: |
BACKGROUND: Untreated microangiopathic hemolytic anemia in pregnancy is associated with adverse maternal and perinatal outcomes. Accurate diagnosis is challenging owing to nonspecific clinical features and pathologic findings. Timely initiation of appropriate management is essential to optimize maternal and perinatal outcomes. CASE: A 26-year-old primiparous woman presented at 20 weeks of gestation with new-onset microangiopathic hemolytic anemia on a background of poorly controlled type 1 diabetes. She received eculizumab for presumed atypical hemolytic uremic syndrome. At 24 weeks of gestation, she developed superimposed early-onset preeclampsia; she delivered at 27 weeks of gestation after continuing eculizumab. CONCLUSION(S): Eculizumab may prolong pregnancy in early-onset preeclampsia. Additional research is needed to assess short-term and long-term maternal and newborn outcomes.Copyright © 2019 by the American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved. |
| مصطلحات الفهرس: |
erythrocyte transfusion, estimated glomerular filtration rate, female, fetal well being, fetus lung maturation, fibrin deposition, fibrosing alveolitis, gene, generalized edema/dt [Drug Therapy], generalized edema/si [Side Effect], gestational age, glycemic control, headache/si [Side Effect], hemoglobin blood level, hemolytic uremic syndrome/di [Diagnosis], heterozygote, histopathology, home oxygen therapy, human, human tissue, hyperreflexia/si [Side Effect], hypertension/dt [Drug Therapy], insulin dependent diabetes mellitus/dt [Drug Therapy], insulin treatment, kidney biopsy, kidney function, kidney tubule, lactate dehydrogenase blood level, lethargy, macroalbuminuria, maternal smoking, meningococcosis, missense mutation, onset age, peripheral edema, placenta insufficiency, platelet count, preeclampsia/dt [Drug Therapy], preeclampsia/pc [Prevention], primipara, priority journal, proliferative diabetic retinopathy, prolonged pregnancy, protein urine level, proteinuria, restlessness/si [Side Effect], thrombocyte aggregation, thrombocytopenia, thrombotic thrombocytopenic purpura/di [Diagnosis], vaccination, acetylsalicylic acid/dt [Drug Therapy], albumin/ec [Endogenous Compound], antihypertensive agent/po [Oral Drug Administration], corticosteroid, creatinine/ec [Endogenous Compound], eculizumab/ae [Adverse Drug Reaction], eculizumab/dt [Drug Therapy], eculizumab/iv [Intravenous Drug Administration], furosemide/dt [Drug Therapy], haptoglobin/ec [Endogenous Compound], hemoglobin/ec [Endogenous Compound], insulin/dt [Drug Therapy], lactate dehydrogenase/ec [Endogenous Compound], magnesium sulfate, nifedipine/dt [Drug Therapy], nifedipine/po [Oral Drug Administration], penicillin derivative, placental growth factor/ec [Endogenous Compound], prednisone, protein/ec [Endogenous Compound], urea/ec [Endogenous Compound], vasculotropin receptor 1/ec [Endogenous Compound], CFI gene, hemolytic uremic syndrome/dt [Drug Therapy], adult, antibiotic prophylaxis, antihypertensive therapy, article, atrophy, blurred vision/si [Side Effect], cannabis use, case report, Caucasian, cesarean section, cigarette smoking, clinical article, creatinine urine level, diabetic nephropathy/di [Diagnosis], end stage renal disease, erythrocyte concentrate, Article |
| URL: |
https://repository.monashhealth.org/monashhealthjspui/handle/1/35380Test
Obstetrics and Gynecology
LibKey Link |
| الإتاحة: |
Open access content. Open access content
Copyright 2020 Elsevier B.V., All rights reserved. |
| أرقام أخرى: |
AUSHL oai:repository.monashhealth.org:1/35380
Obstetrics and Gynecology. 134 (6) (pp 1215-1218), 2019. Date of Publication: 01 Dec 2019.
0029-7844
https://repository.monashhealth.org/monashhealthjspui/handle/1/35380Test
31698377 [http://www.ncbi.nlm.nih.gov/pubmed/?term=31698377Test]
631051870
(Lu, Lazarus, Rolnik, Palmer) Department of Obstetrics and Gynecology and Nephrology, Monash Health, Clayton, VIC, Australia
Lu A.B.; angela_b_lu@hotmail.com
1305140687 |
| المصدر المساهم: |
MONASH HEALTH LIBRS
From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: |
edsoai.on1305140687 |
| قاعدة البيانات: |
OAIster |
