مورد إلكتروني
Immunotherapeutic strategies in antiphospholipid syndrome.
| العنوان: | Immunotherapeutic strategies in antiphospholipid syndrome. |
|---|---|
| بيانات النشر: | Blackwell Publishing (E-mail: info@asia.blackpublishing.com.au) Australia 2017-03-11 |
| تفاصيل مُضافة: | Ross L. Buchanan R.R.C. Day J. Hoi A.Y. |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Antiphospholipid syndrome is an autoimmune condition, characterised by the persistent presence of antiphospholipid antibodies and either thrombosis or obstetric morbidity. The cornerstone of therapy is long-term anticoagulation to reduce morbidity and mortality; however, better understanding of the immunological pathways may direct us to develop future therapeutic strategies. We provide an overview of the current understanding of the immunopathogenesis of this perplexing condition and its associated morbidities and current evidence for some of the immunotherapeutic strategies.Copyright © 2017 Royal Australasian College of Physicians |
| مصطلحات الفهرس: | complement factor H/ec [Endogenous Compound], eculizumab/dt [Drug Therapy], heparin/dt [Drug Therapy], hydroxychloroquine/dt [Drug Therapy], lipocortin 5/ec [Endogenous Compound], low molecular weight heparin/dt [Drug Therapy], phosphatidylinositol 3 kinase/ec [Endogenous Compound], rituximab/dt [Drug Therapy], plasmapheresis, anticoagulant therapy, antiphospholipid syndrome/dt [Drug Therapy], antiphospholipid syndrome/et [Etiology], antiphospholipid syndrome/th [Therapy], complement activation, complement deposition, conformational transition, human, immunopathogenesis, immunosuppressive treatment, immunotherapy, priority journal, review, syncytiotrophoblast, complement component C5a/ec [Endogenous Compound], Review |
| URL: | Internal Medicine Journal Click here for full text options LibKey Link |
| الإتاحة: | Open access content. Open access content Copyright 2017 Elsevier B.V., All rights reserved. |
| أرقام أخرى: | AUSHL oai:repository.monashhealth.org:1/38810 Internal Medicine Journal. 47 (3) (pp 250-256), 2017. Date of Publication: 01 Mar 2017. 1444-0903 https://repository.monashhealth.org/monashhealthjspui/handle/1/38810Test 27572264 [http://www.ncbi.nlm.nih.gov/pubmed/?term=27572264Test] 614679148 (Hoi, Ross, Day, Buchanan) Department of Rheumatology, Austin Health, Melbourne, VIC, Australia (Hoi) Department of Rheumatology, Monash Health, Melbourne, VIC, Australia (Hoi) School of Clinical Sciences, Monash University, Melbourne, VIC, Australia Hoi A.Y.; alberta.hoi@austin.org.au 1305109948 |
| المصدر المساهم: | MONASH HEALTH LIBRS From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1305109948 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |