مورد إلكتروني
Different types of dietary fibers trigger specific alterations in composition and predicted functions of colonic bacterial communities in BALB/c mice
| العنوان: | Different types of dietary fibers trigger specific alterations in composition and predicted functions of colonic bacterial communities in BALB/c mice |
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| المصدر: | ISSN: 1664-302X |
| بيانات النشر: | 2017 |
| تفاصيل مُضافة: | Luo, Yuheng Zhang, Ling Li Li, Hua Smidt, Hauke Wright, André Denis G. Zhang, Keying Ding, Xuemei Zeng, Qiufeng Bai, Shiping Wang, Jianping Li, Jian Zheng, Ping Tian, Gang Cai, Jingyi Chen, Daiwen |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | Soluble dietary fibers (SDF) are fermented more than insoluble dietary fibers (IDF), but their effect on colonic bacterial community structure and function remains unclear. Thus, bacterial community composition and function in the colon of BALB/c mice (n = 7) fed with a high level (approximately 20%) of typical SDF, oat-derived β-glucan (G), microcrystalline cellulose (M) as IDF, or their mixture (GM), were compared. Mice in group G showed a lowest average feed intake (p < 0.05) but no change on the average body weight gain (p > 0.05) compared to other groups, which may be associated with the highest concentration of colonic propionate (p < 0.05) in these mice. The bacterial a-diversity of group G was significantly lower than other groups (p < 0.01). In group G, the relative abundance of bacteria belonging to the phylum Bacteroidetes was significantly increased, whereas bacteria from the phylum Firmicutes were significantly decreased (p < 0.01). The core bacteria for different treatments showed distinct differences. Bacteroides, Dehalobacterium, and Prevotella, including known acetogens and carbohydrate fermenting organisms, were significantly increased in relative abundance in group G. In contrast, Adlercreutzia, Odoribacter, and Coprococcus were significantly more abundant in group M, whereas Oscillospira, Desulfovibrio, and Ruminoccaceae, typical hydrogenotrophs equipped with multiple carbohydrate active enzymes, were remarkably enriched in group GM (p < 0.05). The relative abundance of bacteria from the three classes of Proteobacteria, Betaproteobacteria, Gammaproteobacteria (including Enterobacteriaceae) and Deltaproteobacteria, were significantly more abundant in group G, indicating a higher ratio of conditional pathogenic bacteria in mice fed dietary β-glucan in current study. The predicted colonic microbial function showed an enrichment of "Energy metabolism" and "Carbohydrate metabolism" pathways in mice from group G and M, suggesting that the altered ba |
| مصطلحات الفهرس: | 16S high throughput sequencing, BALB/c mice, Colonic bacterial community, Dietary fibers, PICRUSt predicted functions, Article/Letter to editor |
| URL: | |
| الإتاحة: | Open access content. Open access content Wageningen University & Research |
| ملاحظة: | application/pdf Frontiers in Microbiology 8 (2017) ISSN: 1664-302X ISSN: 1664-302X English |
| أرقام أخرى: | NLWUP oai:library.wur.nl:wurpubs/523843 https://library.wur.nl/WebQuery/wurpubs/523843Test 10.3389/fmicb.2017.00966 1200325593 |
| المصدر المساهم: | WUR STAFF PUBNS From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1200325593 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |