مورد إلكتروني
Mechanisms regulating epidermal stem cells.
| العنوان: | Mechanisms regulating epidermal stem cells. |
|---|---|
| المصدر: | EMBO journal, 31 (9 |
| بيانات النشر: | 2012-05 |
| تفاصيل مُضافة: | Beck, Benjamin Blanpain, Cédric |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | The skin epidermis contains different appendages such as the hair follicle and the sebaceous glands. Recent studies demonstrated that several types of stem cells (SCs) exist in different niches within the epidermis and maintain discrete epidermal compartments, but the exact contribution of each SC populations under physiological conditions is still unclear. In addition, the precise mechanisms controlling the balance between proliferation and differentiation of epidermal SC still remain elusive. Recent studies provide new insights into these important questions by showing the contribution of hair follicle SC to the sebaceous lineage and the importance of chromatin modifications and micro-RNAs (miRs) in regulating epidermal SCs renewal and differentiation. In this review, we will discuss the importance of these papers to our understanding of the mechanisms that control epidermal SC functions. Journal Article Review FLWIN SCOPUS: re.j info:eu-repo/semantics/published |
| مصطلحات الفهرس: | Sciences bio-médicales et agricoles, Animals, Epidermis -- cytology -- metabolism, Humans, MicroRNAs -- metabolism, Repressor Proteins -- metabolism, Sebaceous Glands -- cytology -- metabolism, Stem Cells -- cytology -- metabolism, Tumor Suppressor Proteins -- metabolism, epigenetics, keratinocytes, lineage tracing, micro-RNA, stem cells, info:eu-repo/semantics/article, info:ulb-repo/semantics/articlePeerReview, info:ulb-repo/semantics/openurl/article |
| URL: | |
| الإتاحة: | Open access content. Open access content 1 full-text file(s): info:eu-repo/semantics/restrictedAccess |
| ملاحظة: | 1 full-text file(s): application/pdf English |
| أرقام أخرى: | EQY oai:dipot.ulb.ac.be:2013/123127 uri/info:doi/10.1038/emboj.2012.67 uri/info:pii/emboj201267 uri/info:pmid/22433839 uri/info:scp/84860534759 803509537 |
| المصدر المساهم: | UNIVERSITE LIBRE DE BRUXELLES From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.ocn803509537 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |