التفاصيل البيبلوغرافية
| العنوان: |
Binding of [3H]Quinuclidinyl Benzilate to Regions of Rat Pituitary and Hypothalamus |
| المؤلفون: |
Hoover, Donald B., Hancock, John C., Talley, Nancy S. |
| المصدر: |
ETSU Faculty Works. |
| بيانات النشر: |
Digital Commons @ East Tennessee State University. |
| المجموعة: |
East Tennessee State University |
| مصطلحات موضوعية: |
hypothalamus, median eminence, muscarinic receptors, pituitary, quinuclidinyl benzilate, Biomedical Sciences |
| الوصف: |
Muscarinic ligand binding sites in fragments of rat hypothalamus and pituitary were studied using [3H]quinuclidinyl benzilate (QNB). In the hypothalamus, the highest amount of specific QNB binding was to n. paraventricularis and n. dorsomedialis. Specific QNB binding in other hypothalamic regions varied within a relatively narrow range. Fragments of whole pituitary also bound QNB but to a much smaller degree than brain. Pituitary binding of QNB was blocked by atropine but not by hexamethonium or d-tubocurarine. Within the pituitary, specific QNB binding to posterior pituitary was three times greater than to anterior pituitary. These findings are consistent with the operation of cholinergic mechanisms in hypothalamic and pituitary function. |
| Original Identifier: |
oai:dc.etsu.edu:etsu-works-14471 |
| نوع الوثيقة: |
Text |
| DOI: |
10.1016/S0361-9230(81)80049-4 |
| الإتاحة: |
https://dc.etsu.edu/etsu-works/13205Test |
| رقم الانضمام: |
edsndl.ETSU.oai.dc.etsu.edu.etsu.works.14471 |
| قاعدة البيانات: |
Networked Digital Library of Theses & Dissertations |
