A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers

التفاصيل البيبلوغرافية
العنوان:	A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers
المؤلفون:	Christopher D. Putnam, Anjana Srivatsan, Rahul V. Nene, Sandra L. Martinez, Sarah P. Clotfelter, Sara N. Bell, Steven B. Somach, Jorge E.S. de Souza, André F. Fonseca, Sandro J. de Souza, Richard D. Kolodner
المصدر:	Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
بيانات النشر:	Nature Portfolio, 2016.
سنة النشر:	2016
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Here, Richard Kolodner and colleagues use assays in Saccharomyces cerevisiaeto identify 182 genetic modifiers of gross chromosomal rearrangements (GCRs). They also compared these Genome Instability Suppressing (GIS) genes and pathways in human cancer genome, and found many ovarian and colorectal cancer cases have alterations to GIS pathways.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
العلاقة:	https://doaj.org/toc/2041-1723Test
DOI:	10.1038/ncomms11256
الوصول الحر:	https://doaj.org/article/f89534c401544c92a42a58da6b4da8ceTest
رقم الانضمام:	edsdoj.f89534c401544c92a42a58da6b4da8ce
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/ncomms11256