دورية أكاديمية
Bilateral juvenile osteochondrosis dissecans in monozygotic twins: a case report
| العنوان: | Bilateral juvenile osteochondrosis dissecans in monozygotic twins: a case report |
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| المؤلفون: | Luca Bausch, Monika Probst, Lorenz Fritsch, Julian Mehl, Sebastian Siebenlist, Lukas Willinger |
| المصدر: | Journal of Orthopaedic Surgery and Research, Vol 19, Iss 1, Pp 1-6 (2024) |
| بيانات النشر: | BMC, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Orthopedic surgery LCC:Diseases of the musculoskeletal system |
| مصطلحات موضوعية: | Osteochondrosis dissecans, Osteochondral lesion, Femoral condyle, AOCD, JOCD, Orthopedic surgery, RD701-811, Diseases of the musculoskeletal system, RC925-935 |
| الوصف: | Abstract Introduction The etiology of osteochondrosis dissecans (OCD), a chondropathy associated with detachment of the subchondral bone and the overlaying cartilage, is not yet fully understood. While repetitive physical exercise-related stress is usually assumed to be the main risk factor for the occurrence of OCD, genetic predisposition could have an underestimated influence on the development of the disease. Case report We report a case of monozygotic twins with almost identical stages of bilateral osteochondrosis dissecans of the knee joint. In both patients, initially, a unilateral lesion occurred; despite restricted physical exercise, in the further course of the disease a lesion also developed on the contralateral side. While the lesion found most recently demonstrated an ongoing healing process at a 6-month follow-up, the other three lesions showed a natural course of healing under conservative treatment with significant clinical as well as radiological improvements after one year and complete consolidation in magnetic resonance imaging (MRI) after 2 years. Conclusion There could be a genetic component to the development of OCD, although this has not yet been proven. Based on a two-year MRI follow-up, we were able to show the self-limiting characteristics of juvenile osteochondrosis dissecans. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1749-799X |
| العلاقة: | https://doaj.org/toc/1749-799XTest |
| DOI: | 10.1186/s13018-024-04683-2 |
| الوصول الحر: | https://doaj.org/article/ef883b19cdc24f86a4aa53f22504ca8cTest |
| رقم الانضمام: | edsdoj.f883b19cdc24f86a4aa53f22504ca8c |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1749799X |
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| DOI: | 10.1186/s13018-024-04683-2 |