دورية أكاديمية
Use of Skull Vibration-Induced Nystagmus in the Follow-up of Patients With Ménière Disease Treated With Intratympanic Gentamicin
| العنوان: | Use of Skull Vibration-Induced Nystagmus in the Follow-up of Patients With Ménière Disease Treated With Intratympanic Gentamicin |
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| المؤلفون: | Susana Marcos Alonso, Nicole Almeida Ayerve, Chiara Monopoli Roca, Guillermo Coronel Touma, Juan Carlos del Pozo de Dios, Hortensia Sánchez Gómez, Santiago Santa Cruz Ruíz, Ángel Batuecas Caletrío |
| المصدر: | Clinical and Experimental Otorhinolaryngology, Vol 16, Iss 3, Pp 236-243 (2023) |
| بيانات النشر: | Korean Society of Otorhinolaryngology-Head and Neck Surgery, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine LCC:Otorhinolaryngology |
| مصطلحات موضوعية: | pathologic nystagmus, vestibular disease, meniere disease, gentamicin, head impulse test, Medicine, Otorhinolaryngology, RF1-547 |
| الوصف: | Objectives. Ménière disease (MD) is an idiopathic disorder that affects hearing and inner ear balance. Intratympanic gentamicin (ITG) is recognized as an effective treatment for uncontrolled MD characterized by persistent vertigo attacks despite therapy. The video head impulse test (vHIT) and skull vibration-induced nystagmus (SVIN) are validated methods for evaluating vestibular function. A progressive linear relationship has been identified between the slow-phase velocity (SPV) of SVIN determined using a 100-Hz skull vibrator and the gain difference (healthy ear/affected ear) measured by vHIT. The aim of this study was to ascertain whether the SPV of SVIN was associated with the recovery of vestibular function following ITG treatment. Consequently, we sought to determine whether SVIN could predict the onset of new vertigo attacks in patients with MD who were treated with ITG. Methods. A prospective longitudinal case-control study was conducted. Several variables were recorded post-ITG and throughout the follow-up period, followed by statistical analyses. Two groups were compared: patients who experienced vertigo attacks 6 months after ITG and those who did not. Results. The sample comprised 88 patients diagnosed with MD who underwent ITG treatment. Of the 18 patients who experienced recurring vertigo attacks, 15 demonstrated gain recovery in the affected ear. However, all 18 patients exhibited a decrease in the SPV of SVIN. Conclusion. The SPV of SVIN may be more sensitive than vHIT in identifying the recovery of vestibular function following ITG administration. To our knowledge, this is the first study to illustrate the link between a reduction in SPV and the likelihood of vertigo episodes in patients with MD who have been treated with ITG. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1976-8710 2005-0720 |
| العلاقة: | http://www.e-ceo.org/upload/pdf/ceo-2023-00129.pdfTest; https://doaj.org/toc/1976-8710Test; https://doaj.org/toc/2005-0720Test |
| DOI: | 10.21053/ceo.2023.00129 |
| الوصول الحر: | https://doaj.org/article/f8665158b82249dba0da3aed406be477Test |
| رقم الانضمام: | edsdoj.f8665158b82249dba0da3aed406be477 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19768710 20050720 |
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| DOI: | 10.21053/ceo.2023.00129 |