دورية أكاديمية
Cognition is selectively impaired in males with spinal pain: A retrospective analysis of data from the Longitudinal Study of Ageing Danish Twins
| العنوان: | Cognition is selectively impaired in males with spinal pain: A retrospective analysis of data from the Longitudinal Study of Ageing Danish Twins |
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| المؤلفون: | David C. Byfield, Benjamin S. Stacey, Damian M. Bailey |
| المصدر: | Experimental Physiology, Vol 109, Iss 4, Pp 474-483 (2024) |
| بيانات النشر: | Wiley, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Physiology |
| مصطلحات موضوعية: | cognitive function, dementia, neuroinflammation, physical inactivity, spinal pain, Physiology, QP1-981 |
| الوصف: | Abstract Cognitive decline and spinal pain (back pain [BP] and neck pain [NP]) represent a major public health challenge, yet the potential relationship between them remains elusive. A retrospective analysis of the Longitudinal Study of Ageing Danish Twins was performed to determine any potential relationships between BP/NP and cognitive function adjusting for age, sex, educational and socioeconomic status. A total of 4731 adults (2788 females/1943 males) aged 78 ± 6 (SD) years were included in the analysis. We observed a 1‐month prevalence of 25% with BP, 21% with NP and 11% for combined BP/NP. While there were no differences in cognition scores for males and females reporting combined BP/NP, compared to those without combined BP/NP (34.38 points [95% confidence interval (CI) = 31.88, 36.88] vs. 35.72 points [95% CI = 35.19, 36.26]; P = 0.180; and 35.72 points [95% CI = 35.19, 36.26] vs. 35.85 points [95% CI = 35.39, 36.31]; P = 0.327; for male and females, respectively), an adjusted analysis revealed that males with combined BP/NP presented with lower cognitive scores compared to males without combined BP/NP (81.26 points [95% CI = 73.80, 88.72] vs. 79.48 points [95% CI = 70.31, 88.66]; P = 0.043). The findings of this hypothesis‐generating study may highlight a potential sex‐specific association between spinal pain and later‐life neurodegeneration. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1469-445X 0958-0670 |
| العلاقة: | https://doaj.org/toc/0958-0670Test; https://doaj.org/toc/1469-445XTest |
| DOI: | 10.1113/EP091177 |
| الوصول الحر: | https://doaj.org/article/f0520b1e10fe411bb02e3ec1540015e4Test |
| رقم الانضمام: | edsdoj.f0520b1e10fe411bb02e3ec1540015e4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1469445X 09580670 |
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| DOI: | 10.1113/EP091177 |