دورية أكاديمية

The role of serum IL-6 changes in evaluation of endometriosis

التفاصيل البيبلوغرافية
العنوان: The role of serum IL-6 changes in evaluation of endometriosis
المؤلفون: Tharwa H. Hassan AL-Tai, Hayfaa S. AL-Hadithi, Hind S. Abdulsalam
المصدر: مجلة كلية الطب, Vol 55, Iss 2 (2013)
بيانات النشر: College of Medicine University of Baghdad, 2013.
سنة النشر: 2013
المجموعة: LCC:Medicine
LCC:Medicine (General)
مصطلحات موضوعية: Endometriosis, IL-6., Medicine, Medicine (General), R5-920
الوصف: Background:- Endometriosis is a common chronic gynecological disorder characterized by the presence and proliferation of functional endometrial gland and stroma outside the uterine cavity, affecting approximately 10% of reproductive age women. Il-6 level increased in the patient with endometriosis. Objective:- Evaluate the correlation of IL-6 levels with the degree of severity of endometriosis Patients and methods:- In this study, 84 samples 51women with endometriosis (20 newly diagnosed and 31 treated cases) and 33 of healthy control group, were collected starting from November 2011 to end of January 2012, to investigate the IL-6 serum level by using ELISA kit. Results :- Endometriosis patients mainly presented at the age between (28-37). IL-6 serum levels were significantly decrease in those with stage IV endometriosis. Also appear to be significantly affected by the use of danazol or zoladex treatment of endometriosis and remain low even in treated patients. Serum IL-6 test was highly specific but with low sensitivity. Conclusion:-Serum IL-6 concentration seem to be the highly specific test that can be used as an early detection marker for endometriosis.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 0041-9419
2410-8057
العلاقة: http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/view/646Test; https://doaj.org/toc/0041-9419Test; https://doaj.org/toc/2410-8057Test
DOI: 10.32007/jfacmedbagdad.v2158-161%
الوصول الحر: https://doaj.org/article/abd72f292e17462d80828c1197767716Test
رقم الانضمام: edsdoj.bd72f292e17462d80828c1197767716
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:00419419
24108057
DOI:10.32007/jfacmedbagdad.v2158-161%