دورية أكاديمية
Chemical Pleurodesis Using Tetracycline for the Management of Postoperative Pneumothorax Recurrence
| العنوان: | Chemical Pleurodesis Using Tetracycline for the Management of Postoperative Pneumothorax Recurrence |
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| المؤلفون: | Jun Tae Yang, Sahri Kim, Hyoung Soo Kim, Hee Sung Lee, Yong Joon Ra, Hong Kyu Lee |
| المصدر: | Journal of Chest Surgery, Vol 56, Iss 4, Pp 240-243 (2023) |
| بيانات النشر: | Korean Society for Thoracic & Cardiovascular Surgery, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Medicine (General) |
| مصطلحات موضوعية: | lung, pneumothorax, recurrence, pleurodesis, tetracycline, Medicine (General), R5-920 |
| الوصف: | Background: Although there is no obvious recommendation for the management of pneumothorax recurrence after surgery, chemical pleurodesis with tetracycline has been applied as a significant treatment approach. The objective of this study was to evaluate the effectiveness of chemical pleurodesis with tetracycline for the management of postoperative recurrence of primary spontaneous pneumothorax (PSP). Methods: We retrospectively analyzed patients who underwent video-assisted thoracic surgery (VATS) as therapy for PSP at Hallym University Sacred Heart Hospital from January 2010 to December 2016. Patients who had ipsilateral recurrence after surgery were included in this study. Patients who underwent pleural drainage with chemical pleurodesis were compared with patients who only underwent pleural drainage. Results: In total, 932 patients who underwent VATS for PSP were analyzed, and ipsilateral recurrence after surgery occurred in 67 patients (7.1%). The treatment modalities for recurrence after surgery were observation (n=12), pleural drainage alone (n=16), pleural drainage with chemical pleurodesis (n=34), and repeated VATS (n=5). Eight of the 16 patients (50 %) treated with pleural drainage alone had recurrence again, while 15 of the 34 patients (44.1%) treated with pleural drainage and chemical pleurodesis experienced further recurrence. Chemical pleurodesis with tetracycline did not show a meaningful difference in the re-recurrence rate in comparison with pleural drainage alone (p=0.332). Conclusion: Chemical pleurodesis with tetracycline for the management of postoperative recurrence of PSP was not effective. Further research is required to identify alternative drugs that can significantly decrease the re-recurrence rate. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2765-1606 2765-1614 |
| العلاقة: | https://doaj.org/toc/2765-1606Test; https://doaj.org/toc/2765-1614Test |
| DOI: | 10.5090/jcs.23.006 |
| الوصول الحر: | https://doaj.org/article/b972ca36dc0d44ec9a36078290a7fd53Test |
| رقم الانضمام: | edsdoj.b972ca36dc0d44ec9a36078290a7fd53 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 27651606 27651614 |
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| DOI: | 10.5090/jcs.23.006 |