دورية أكاديمية
Modified application of SAMe-TTR scoring system in Asian patients with atrial fibrillation for the selection of oral anticoagulants
| العنوان: | Modified application of SAMe-TTR scoring system in Asian patients with atrial fibrillation for the selection of oral anticoagulants |
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| المؤلفون: | Seong Won Jeon, Nuri Lee, Ki Hong Lee, Minjeong Ha, Changhyun Kim, Yoo Ri Kim, Nam Sik Yoon, Hyung Wook Park |
| المصدر: | The Korean Journal of Internal Medicine, Vol 39, Iss 3, Pp 458-468 (2024) |
| بيانات النشر: | The Korean Association of Internal Medicine, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | warfarin, prothrombin time, atrial fibrillation, thromboembolism, safety, Medicine |
| الوصف: | Background/Aims The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those populations. This study aimed to validate the SAMe-TT2R2 score in Asian patients with AF and suggest a modified SAMe-TT2R2 score for this population. Methods We analyzed 710 Korean patients with AF who were using warfarin. The AC quality was assessed as the mean time in therapeutic range (TTR). Each component of SAMe-TT2R2 score was evaluated for the relationship with AC. Further clinical factors that predict AC were analyzed. Identified factors were re-assorted and constructed as SA2Me-TTR scoring system. Results Of the components of the SAMe-TT2R2 score, female, age, and rhythm control were associated with AC. Heart failure and renal insufficiency were newly identified factors associated with AC. The modified SA2Me-TTR score was reconstructed with the relevant risk factors (S, female gender, 1 point; A, age < 60 yr, 2 points; Me, medical history of heart failure, 1 point; T, treatment for rhythm control, 1 point; T, history of stroke or transient ischemic attack, 1 point; R, renal insufficiency, 1 point). The modified SA2Me-TTR score demonstrated an excellent relationship with the grading of AC. The modified SA2Me-TTR score ≤ 1 identified patients with good AC (hazard ratio 2.46, 95% CI 1.75–3.47). Conclusions The modified SA2Me-TTR score was useful for guiding oral anticoagulants selection in Asian patients with AF. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1226-3303 2005-6648 |
| العلاقة: | http://www.kjim.org/upload/kjim-2023-381.pdfTest; https://doaj.org/toc/1226-3303Test; https://doaj.org/toc/2005-6648Test |
| DOI: | 10.3904/kjim.2023.381 |
| الوصول الحر: | https://doaj.org/article/b62b08761f81458cacc25a6797aba788Test |
| رقم الانضمام: | edsdoj.b62b08761f81458cacc25a6797aba788 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 12263303 20056648 |
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| DOI: | 10.3904/kjim.2023.381 |