التفاصيل البيبلوغرافية
العنوان:
Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection
المؤلفون:
Emily Adland , Jane Millar , Nomonde Bengu , Maximilian Muenchhoff , Rowena Fillis , Kenneth Sprenger , Vuyokasi Ntlantsana , Julia Roider , Vinicius Vieira , Katya Govender , John Adamson , Nelisiwe Nxele , Christina Ochsenbauer , John Kappes , Luisa Mori , Jeroen van Lobenstein , Yeney Graza , Kogielambal Chinniah , Constant Kapongo , Roopesh Bhoola , Malini Krishna , Philippa C. Matthews , Ruth Penya Poderos , Marta Colomer Lluch , Maria C. Puertas , Julia G. Prado , Neil McKerrow , Moherndran Archary , Thumbi Ndung’u , Andreas Groll , Pieter Jooste , Javier Martinez-Picado , Marcus Altfeld , Philip Goulder
المصدر:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
بيانات النشر:
Nature Portfolio, 2020.
سنة النشر:
2020
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Sex differences in the immune response to vaccines and infections have been well described in children and adults. Here the authors describe, in a cohort of 177 HIV-infected infants, innate immune sex differences in fetal life that increase female susceptibility to intrauterine HIV infection and increase the chances of subsequent HIV remission in infected males.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-020-15632-y
الوصول الحر:
https://doaj.org/article/b55696a6d6ee44ba9f20d18889681d90Test
رقم الانضمام:
edsdoj.b55696a6d6ee44ba9f20d18889681d90
قاعدة البيانات:
Directory of Open Access Journals