دورية أكاديمية
Impact of Time-Restricted Feeding on Adaptation to a 6-Hour Delay Phase Shift or a 12-Hour Phase Shift in Mice
العنوان: | Impact of Time-Restricted Feeding on Adaptation to a 6-Hour Delay Phase Shift or a 12-Hour Phase Shift in Mice |
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المؤلفون: | Baoyin Ren, Yingzhi Huang, Jiayang Zhang, Jiazhi Li, Zhaiyi Liu, Youfei Guan, Lihong Chen, Guangrui Yang |
المصدر: | Nutrients, Vol 14, Iss 15, p 3025 (2022) |
بيانات النشر: | MDPI AG, 2022. |
سنة النشر: | 2022 |
المجموعة: | LCC:Nutrition. Foods and food supply |
مصطلحات موضوعية: | adaptation, behavior, phase shift, sepsis, time-restricted feeding, Nutrition. Foods and food supply, TX341-641 |
الوصف: | Nowadays, more and more people are suffering from circadian disruption. However, there is no well-accepted treatment. Recently, time-restricted feeding (TRF) was proposed as a potential non-drug intervention to alleviate jet lag in mice, especially in mice treated with a 6-h advanced phase shift. Here, we challenged C57BL/6 mice with a 6-h delay phase shift or a 12-h shift (day-night reversal) combined with 6- or 12-h TRF within the dark phase and found the beneficial effects of given TRF strategies in certain phase-shifting situations. Although behavioral fitness did not correlate well with health status, none of the TRF strategies we used deteriorated lipopolysaccharide-induced sepsis. These findings improve our understanding of the benefits of TRF for adaptation to circadian disruption. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 14153025 2072-6643 |
العلاقة: | https://www.mdpi.com/2072-6643/14/15/3025Test; https://doaj.org/toc/2072-6643Test |
DOI: | 10.3390/nu14153025 |
الوصول الحر: | https://doaj.org/article/b517831a11ff4d199c42d75c5453a6e9Test |
رقم الانضمام: | edsdoj.b517831a11ff4d199c42d75c5453a6e9 |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 14153025 20726643 |
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DOI: | 10.3390/nu14153025 |