دورية أكاديمية
Self-control is associated with health-relevant disparities in buccal DNA-methylation measures of biological aging in older adults
| العنوان: | Self-control is associated with health-relevant disparities in buccal DNA-methylation measures of biological aging in older adults |
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| المؤلفون: | Y. E. Willems, A. deSteiguer, P. T. Tanksley, L. Vinnik, D. Fraemke, A. Okbay, D. Richter, G. G. Wagner, R. Hertwig, P. Koellinger, E. M. Tucker-Drob, K. P. Harden, Laurel Raffington |
| المصدر: | Clinical Epigenetics, Vol 16, Iss 1, Pp 1-13 (2024) |
| بيانات النشر: | BMC, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Genetics |
| مصطلحات موضوعية: | Self-control, DNA-methylation, Pace of aging, Biological aging, Health, Life span, Medicine, Genetics, QH426-470 |
| الوصف: | Abstract Self-control is a personality dimension that is associated with better physical health and a longer lifespan. Here, we examined (1) whether self-control is associated with buccal and saliva DNA-methylation (DNAm) measures of biological aging quantified in children, adolescents, and adults, and (2) whether biological aging measured in buccal DNAm is associated with self-reported health. Following preregistered analyses, we computed two DNAm measures of advanced biological age (principal-component PhenoAge and GrimAge Acceleration) and a DNAm measure of pace of aging (DunedinPACE) in buccal samples from the German Socioeconomic Panel Study (SOEP-G[ene], n = 1058, age range 0–72, M age = 42.65) and saliva samples from the Texas Twin Project (TTP, n = 1327, age range 8–20, M age = 13.50). We found that lower self-control was associated with advanced biological age in older adults (PhenoAge Acceleration β = − .34, [− .51, − .17], p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1868-7083 |
| العلاقة: | https://doaj.org/toc/1868-7083Test |
| DOI: | 10.1186/s13148-024-01637-7 |
| الوصول الحر: | https://doaj.org/article/deb487244a0c440585528d47fc2f64eeTest |
| رقم الانضمام: | edsdoj.b487244a0c440585528d47fc2f64ee |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 18687083 |
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| DOI: | 10.1186/s13148-024-01637-7 |