دورية أكاديمية
The long-term surgical outcomes of conjunctival-limbal autograft procedure with or without penetrating keratoplasty in eyes with unilateral limbal stem cell deficiency
| العنوان: | The long-term surgical outcomes of conjunctival-limbal autograft procedure with or without penetrating keratoplasty in eyes with unilateral limbal stem cell deficiency |
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| المؤلفون: | Muhammet Derda Ozer, Emre Altinkurt, Nilufer Alparslan |
| المصدر: | Taiwan Journal of Ophthalmology, Vol 10, Iss 1, Pp 22-28 (2020) |
| بيانات النشر: | Wolters Kluwer Medknow Publications, 2020. |
| سنة النشر: | 2020 |
| المجموعة: | LCC:Ophthalmology |
| مصطلحات موضوعية: | chemical injury, conjunctival-limbal autograft transplantation, eyelid reconstruction, limbal stem cell deficiency, penetrating keratoplasty, Ophthalmology, RE1-994 |
| الوصف: | AIM: The aim of the study is to report the results of conjunctival-limbal autograft (CLAU) transplantation and penetrating keratoplasty (PK) in eyes with limbal stem cell deficiency (LSCD) due to chemical or thermal injury. METHODS: Thirty-one eyes of the 31 patients, who had unilateral LSCD due to chemical or thermal injury, were included in the study. Bilaterally affected cases and LSCD due to Steven-Johnson syndrome and mucous membrane pemphigoid were excluded from the study. All patients underwent a complete ophthalmologic examination. The surgical procedures, postoperative complications, ocular surface status, and visual outcomes were noted. RESULTS: In the CLAU group, regular corneal epithelium and ambulatory vision (≤1.0 logarithm of the minimum angle of resolution [20/200]) were achieved in 81% of eyes, including 22 eyes (71%) that were assessed after a mean follow-up period of 58 months, respectively. The 5-year survival rate of corneal allograft was 33%, 4 ± 13.9 in the CLAU applied eyes. In addition, the corneal graft clarity maintenance rate was found to be higher in patients having ≥12 months duration between CLAU and PK, which is statistically significant (62% vs. 23%,P = 0.046). CONCLUSION: Waiting at least 1 year after CLAU transplantation to perform PK increases corneal clarity. Eyelid problems, even if the eyelids were reconstructed properly, remain a major risk factor for the development of the epithelial disorder in the early and late postoperative period in CLAU applied eyes. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2211-5056 2211-5072 |
| العلاقة: | http://www.e-tjo.org/article.asp?issn=2211-5056;year=2020;volume=10;issue=1;spage=22;epage=28;aulast=OzerTest; https://doaj.org/toc/2211-5056Test; https://doaj.org/toc/2211-5072Test |
| DOI: | 10.4103/tjo.tjo_55_19 |
| الوصول الحر: | https://doaj.org/article/9daf77200ba44843ad5279daba59cfd4Test |
| رقم الانضمام: | edsdoj.9daf77200ba44843ad5279daba59cfd4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 22115056 22115072 |
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| DOI: | 10.4103/tjo.tjo_55_19 |