دورية أكاديمية
Immunomodulatory effects of topical diphencyprone for the treatment of acute urban cutaneous leishmaniasis
| العنوان: | Immunomodulatory effects of topical diphencyprone for the treatment of acute urban cutaneous leishmaniasis |
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| المؤلفون: | Yalda Nahidi, Vahid Mashayekhi Goyonlo, Pouran Layegh, Faezeh Taghavi, Mona Najaf Najafi |
| المصدر: | Journal of Dermatological Treatment, Vol 32, Iss 2, Pp 220-226 (2021) |
| بيانات النشر: | Taylor & Francis Group, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Dermatology |
| مصطلحات موضوعية: | diphencyprone, cutaneous leishmaniasis, meglumine antimoniate, diphenylcyclopropenone, Dermatology, RL1-803 |
| الوصف: | Background and objective Efficacious and safe treatments are lacking for cutaneous leishmaniasis (CL). This study investigates the efficacy of adding diphencyprone immunotherapy to conventional meglumine antimoniate (MA) treatment for acute urban CL. Methods This randomized controlled pilot study included 46 patients with acute CL. They were randomly allocated to receive either combination of diphencyprone immunotherapy with intralesional MA (intervention; N = 23) or intralesional MA alone (control; N = 23) weekly. The size and duration of lesions were measured at the baseline and after that at 4th, 8th, 12th, and 24th weeks. Data were analyzed in SPSS and p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0954-6634 1471-1753 09546634 |
| العلاقة: | https://doaj.org/toc/0954-6634Test; https://doaj.org/toc/1471-1753Test |
| DOI: | 10.1080/09546634.2019.1642997 |
| الوصول الحر: | https://doaj.org/article/9d4ea4f6b9b6468592da47aa4e4dbb69Test |
| رقم الانضمام: | edsdoj.9d4ea4f6b9b6468592da47aa4e4dbb69 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 09546634 14711753 |
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| DOI: | 10.1080/09546634.2019.1642997 |