دورية أكاديمية
Clinicopathological Characteristics and Disease-Free Survival in Patients with Hürthle Cell Carcinoma: A Multicenter Cohort Study in South Korea
| العنوان: | Clinicopathological Characteristics and Disease-Free Survival in Patients with Hürthle Cell Carcinoma: A Multicenter Cohort Study in South Korea |
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| المؤلفون: | Meihua Jin, Eun Sook Kim, Bo Hyun Kim, Hee Kyung Kim, Yea Eun Kang, Min Ji Jeon, Tae Yong Kim, Ho-Cheol Kang, Won Bae Kim, Young Kee Shong, Mijin Kim, Won Gu Kim |
| المصدر: | Endocrinology and Metabolism, Vol 36, Iss 5, Pp 1078-1085 (2021) |
| بيانات النشر: | Korean Endocrine Society, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Diseases of the endocrine glands. Clinical endocrinology |
| مصطلحات موضوعية: | thyroid cancer, hurthle cell carcinoma, ultrasonography, prognosis, recurrence, Diseases of the endocrine glands. Clinical endocrinology, RC648-665 |
| الوصف: | Background Hürthle cell carcinoma (HCC), a type of thyroid carcinoma, is rare in South Korea, and few studies have investigated its prognosis. Methods This long-term multicenter retrospective cohort study evaluated the clinicopathological features and clinical outcomes in patients with HCC who underwent thyroid surgery between 1996 and 2009. Results The mean age of the 97 patients included in the study was 50.3 years, and 26.8% were male. The mean size of the primary tumor was 3.2±1.8 cm, and three (3.1%) patients had distant metastasis at initial diagnosis. Ultrasonographic findings were available for 73 patients; the number of nodules with low-, intermediate-, and high suspicion was 28 (38.4%), 27 (37.0%), and 18 (24.7%), respectively, based on the Korean-Thyroid Imaging Reporting and Data System. Preoperatively, follicular neoplasm (FN) or suspicion for FN accounted for 65.2% of the cases according to the Bethesda category, and 13% had malignancy or suspicious for malignancy. During a median follow-up of 8.5 years, eight (8.2%) patients had persistent/recurrent disease, and none died of HCC. Older age, gross extrathyroidal extension (ETE), and widely invasive types of tumors were significantly associated with distant metastasis (all P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English Korean |
| تدمد: | 2093-596X 2093-5978 |
| العلاقة: | http://www.e-enm.org/upload/pdf/enm-2021-1151.pdfTest; https://doaj.org/toc/2093-596XTest; https://doaj.org/toc/2093-5978Test |
| DOI: | 10.3803/EnM.2021.1151 |
| الوصول الحر: | https://doaj.org/article/9b6ff342134e4302b522c3eace43c6deTest |
| رقم الانضمام: | edsdoj.9b6ff342134e4302b522c3eace43c6de |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2093596X 20935978 |
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| DOI: | 10.3803/EnM.2021.1151 |