Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains

التفاصيل البيبلوغرافية
العنوان:	Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains
المؤلفون:	Gabriel E. Hoffman, Brigham J. Hartley, Erin Flaherty, Ian Ladran, Peter Gochman, Douglas M. Ruderfer, Eli A. Stahl, Judith Rapoport, Pamela Sklar, Kristen J. Brennand
المصدر:	Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
بيانات النشر:	Nature Portfolio, 2017.
سنة النشر:	2017
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Induced pluripotent stem cell (hiPSC)-based models have inherent variations in their cellular and molecular output and readouts. Here, Hoffman and colleagues devise a method to account for gene expression variations in hiPSC-derived neurons from patients with childhood-onset schizophrenia.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
العلاقة:	https://doaj.org/toc/2041-1723Test
DOI:	10.1038/s41467-017-02330-5
الوصول الحر:	https://doaj.org/article/99c9b01d94b044f2bf2ad26960baaf9fTest
رقم الانضمام:	edsdoj.99c9b01d94b044f2bf2ad26960baaf9f
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-017-02330-5