دورية أكاديمية

Validation of a Probabilistic Prediction Model for Patients with Type 1 Diabetes Using Compositional Data Analysis

التفاصيل البيبلوغرافية
العنوان: Validation of a Probabilistic Prediction Model for Patients with Type 1 Diabetes Using Compositional Data Analysis
المؤلفون: Alvis Cabrera, Lyvia Biagi, Aleix Beneyto, Ernesto Estremera, Iván Contreras, Marga Giménez, Ignacio Conget, Jorge Bondia, Josep Antoni Martín-Fernández, Josep Vehí
المصدر: Mathematics, Vol 11, Iss 5, p 1241 (2023)
بيانات النشر: MDPI AG, 2023.
سنة النشر: 2023
المجموعة: LCC:Mathematics
مصطلحات موضوعية: compositional data, continuous glucose monitoring, prediction model, time in range, type 1 diabetes, Mathematics, QA1-939
الوصف: Glycemia assessment in people with type 1 diabetes (T1D) has focused on the time spent in different glucose ranges. As this time reflects the relative contributions to the finite duration of a day, it should be treated as compositional data (CoDa) that can be applied to T1D data. Previous works presented a tool for the individual categorization of days and proposed a probabilistic transition model between categories, although validation has hitherto not been presented. In this study, we consider data from eight real adult patients with T1D obtained from continuous glucose monitoring (CGM) sensors and introduce a methodology based on compositional methods to validate the previously presented probability transition model. We conducted 5-fold cross-validation, with both the training and validation data being CoDa vectors, which requires developing new performance metrics. We design new accuracy and precision measures based on statistical error calculations. The results show that the precision for the entire model is higher than 95% in all patients. The use of a probabilistic transition model can help doctors and patients in diabetes treatment management and decision-making. Although the proposed method was tested with CoDa applied to T1D data obtained from CGM, the newly developed accuracy and precision measures apply to any other data or validation based on CoDa.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 2227-7390
العلاقة: https://www.mdpi.com/2227-7390/11/5/1241Test; https://doaj.org/toc/2227-7390Test
DOI: 10.3390/math11051241
الوصول الحر: https://doaj.org/article/9838982cf7b441e7b33d935a43bfc373Test
رقم الانضمام: edsdoj.9838982cf7b441e7b33d935a43bfc373
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:22277390
DOI:10.3390/math11051241