BAD regulates mammary gland morphogenesis by 4E-BP1-mediated control of localized translation in mouse and human models

التفاصيل البيبلوغرافية
العنوان:	BAD regulates mammary gland morphogenesis by 4E-BP1-mediated control of localized translation in mouse and human models
المؤلفون:	John Maringa Githaka, Namita Tripathi, Raven Kirschenman, Namrata Patel, Vrajesh Pandya, David A. Kramer, Rachel Montpetit, Lin Fu Zhu, Nahum Sonenberg, Richard P. Fahlman, Nika N. Danial, D. Alan Underhill, Ing Swie Goping
المصدر:	Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
بيانات النشر:	Nature Portfolio, 2021.
سنة النشر:	2021
المجموعة:	LCC:Science
مصطلحات موضوعية:	Science
الوصف:	Preventing phosphorylation of BAD (3SA) in mouse models and human cells inhibits mammary gland development, acting by disrupting 4E-BP1- mediated translation and affecting focal adhesion/protrusion stability, cell migration and ductal tubulogenesis.
نوع الوثيقة:	article
وصف الملف:	electronic resource
اللغة:	English
تدمد:	2041-1723
العلاقة:	https://doaj.org/toc/2041-1723Test
DOI:	10.1038/s41467-021-23269-8
الوصول الحر:	https://doaj.org/article/da9677ace6fa4ee0a7b417531c2a2ab1Test
رقم الانضمام:	edsdoj.9677ace6fa4ee0a7b417531c2a2ab1
قاعدة البيانات:	Directory of Open Access Journals

الوصف
تدمد:	20411723
DOI:	10.1038/s41467-021-23269-8