دورية أكاديمية
Role of innate immunity in SARS-CoV-2 infection
| العنوان: | Role of innate immunity in SARS-CoV-2 infection |
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| المؤلفون: | Zihao Wang, Fang Cheng, Yuxiu Xu, Xin Li, Songdong Meng |
| المصدر: | Biosafety and Health, Vol 5, Iss 5, Pp 280-288 (2023) |
| بيانات النشر: | Elsevier, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Infectious and parasitic diseases LCC:Public aspects of medicine |
| مصطلحات موضوعية: | Innate immunity, SARS-CoV-2, Traditional Chinese medicine, Depression, Heat shock protein, Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270 |
| الوصف: | During severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, activated macrophages, dendritic cells (D.C.), neutrophils, and natural killer (N.K.) cells are the first defense against infection. These immune effectors trap and ingest the virus, kill infected epithelial cells, or produce anti-viral cytokines. Evidence suggests that aging, obesity, and mental illness can lead to weakened innate immunity and, thus, are all associated with elevated infection and severe disease progression of coronavirus disease 2019 (COVID-19). Innate immune defense networks play a fundamental role in suppressing viral replication, infection establishment, and viral pathogenesis of SARS-CoV-2 and other respiratory viruses. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2590-0536 |
| العلاقة: | http://www.sciencedirect.com/science/article/pii/S2590053623001076Test; https://doaj.org/toc/2590-0536Test |
| DOI: | 10.1016/j.bsheal.2023.08.005 |
| الوصول الحر: | https://doaj.org/article/960048f50ba74ffc8c123c61ce1f3e83Test |
| رقم الانضمام: | edsdoj.960048f50ba74ffc8c123c61ce1f3e83 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 25900536 |
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| DOI: | 10.1016/j.bsheal.2023.08.005 |