دورية أكاديمية
Physicochemical, Antimicrobial, Lethality and In Vitro Antioxidant Profiles of Johnu Tisane: A Coffee (Coffea Arabica) Leaf Decoction Formula
| العنوان: | Physicochemical, Antimicrobial, Lethality and In Vitro Antioxidant Profiles of Johnu Tisane: A Coffee (Coffea Arabica) Leaf Decoction Formula |
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| المؤلفون: | Anthony Cemaluk Chinedum Egbuonu, Prince Ogochukwu Alaebo, Udumma Nsofor Onuoha, Chinomso Juliet Njoku, Chiemeziem Adanma Obike, Susan Ogechi Nlemadim, Blessing Ifeoma Chukwu, Sopuruchi Mary-Augusta Iwejuo, Onyedikachi Glory Amaechi, Victor Ifechukwu Obiefuna, Bessing Nmesomachi Onuoha, DivineTreasure Nzubechukwu Okoli, Precious Chinonso Nwokeoma, Chukwubuikem Eze |
| المصدر: | Biology, Medicine & Natural Product Chemistry, Vol 13, Iss 1, Pp 99-107 (2024) |
| بيانات النشر: | State Islamic University Sunan Kalijaga, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Biology (General) |
| مصطلحات موضوعية: | in-vivo anti-oxidative outcomes and roles, johnu tisane, requisite physicochemical mix, requisite anti-oxidant capacity, rich phyto-constituents-related diverse pharmacologic activities, Biology (General), QH301-705.5 |
| الوصف: | Coffee leaves-based tea has relevance in ethno-medications due to its rich phyto-constituents-related diverse pharmacologic activities. Jonhu tisane, a typical Coffea arabica leaf decoction has no supporting scientific basis amidst reported location, processing and specie-related variations. This investigated physicochemical, antimicrobial, lethality and in-vitro antioxidant profiles of Johnu tisane by acceptable methods. Results recorded moisture (92.26 %), ash (0.65 %), unsaponified matter (1.46 mg/100 g), free fatty acid (0.56 mgKOH/g), acid value (1.12 mgKOH/g), potential hydrogen (6.85), lethal concentration (1000 ppm) and concentration-dependent antimicrobial activity. Anti-oxidation results revealed total antioxidant capacity, ferric reducing antioxidant power, nitric oxide, hydrogen peroxide and 2, 2-diphynyl-1-picrylhydrazyl scavenging activities increased concentration-dependently compared to standard. Thus, Johnu tisane demonstrated low minerals and keeping quality; requisite physicochemical mix for consumption and bioactivity; high safety margin; antimicrobial potency; and requisite anti-oxidation capacity for in-vivo antioxidant role. These provided scientific support for its ethno-medicinal uses. They underscored the need to elucidate its pharmacologically active compounds; mechanistic roles in animal models; and the impact of ash to moisture mix variation on potential hydrogen, microbial and antimicrobial activities in relation to shelf life, bioactivity and in vivo anti-oxidative roles for novel insights on preserving sample quality, safety, bioactivity and in-vivo anti-oxidative outcomes. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2089-6514 2540-9328 |
| العلاقة: | https://sciencebiology.org/index.php/BIOMEDICH/article/view/462Test; https://doaj.org/toc/2089-6514Test; https://doaj.org/toc/2540-9328Test |
| DOI: | 10.14421/biomedich.2024.131.99-107 |
| الوصول الحر: | https://doaj.org/article/ae95f7c9dd3d49aab9e6d9de4e1a587bTest |
| رقم الانضمام: | edsdoj.95f7c9dd3d49aab9e6d9de4e1a587b |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 20896514 25409328 |
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| DOI: | 10.14421/biomedich.2024.131.99-107 |