Tuberculosis (TB) is one of the leading causes of death throughout the world. Traditional medicine poses a serious challenge to drug resistance against Mycobacterium tuberculosis. Hence, it is an urgent need to develop, novel the anti-mycobacterial compounds. In this study, a potent anti-mycobacterial compound producing Staphylococcus hominis IS2 was isolated from the custard apple exhibiting novel anti-mycobacterial activity than other isolates. The bacterial strain was cultured and anti-mycobacterial compound was purified by the combination of ammonium sulphate precipitation and DEAE-cellulose column chromatography. The purified protein corresponding to 10 kDa presented anti-mycobacterial activity. It was further characterized and the difference in activity towards temperature and pH was observed (p
Full Text Finder