دورية أكاديمية
Ischemia-modified albumin: a novel blood marker of endoscopic mucosal healing in inflammatory bowel disease
| العنوان: | Ischemia-modified albumin: a novel blood marker of endoscopic mucosal healing in inflammatory bowel disease |
|---|---|
| المؤلفون: | Seung Bum Lee, Hyun-Ki Kim, Sang Hyuk Park, Ji-Hun Lim, Sang Hyoung Park |
| المصدر: | Intestinal Research, Vol 22, Iss 1, Pp 75-81 (2024) |
| بيانات النشر: | Korean Association for the Study of Intestinal Diseases, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine LCC:Diseases of the digestive system. Gastroenterology |
| مصطلحات موضوعية: | inflammatory bowel diseases, biomarkers, endoscopy, Medicine, Diseases of the digestive system. Gastroenterology, RC799-869 |
| الوصف: | Background/Aims The achievement of endoscopic remission is an important therapeutic goal in the treatment of inflammatory bowel diseases (IBD). We aimed to evaluate the role of fecal calprotectin (FCP) and ischemia-modified albumin (IMA) as biomarkers for evaluating IBD disease activity. Methods A total of 48 patients with IBD (20 with ulcerative colitis and 28 with Crohn’s disease) were included in this study. FCP and serum C-reactive protein levels, erythrocyte sedimentation rate, and IMA were measured in patients with IBD and compared with endoscopic findings. Results Elevated FCP and serum IMA levels were significantly associated with endoscopic non-mucosal healing. The correlation between FCP and IMA was not significant. Analysis of the receiver operating characteristic curve showed that both FCP and IMA had diagnostic value in predicting non-mucosal healing. When the Ln(FCP)+IMA/10 value was calculated using both factors, the predictive value for non-mucosal healing increased; however, no significant difference was observed. Conclusions IMA could be a candidate serum biomarker for predicting endoscopic mucosal healing in IBD. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1598-9100 2288-1956 25780441 |
| العلاقة: | http://irjournal.org/upload/pdf/ir-2023-00065.pdfTest; https://doaj.org/toc/1598-9100Test; https://doaj.org/toc/2288-1956Test |
| DOI: | 10.5217/ir.2023.00065 |
| الوصول الحر: | https://doaj.org/article/9119a5d2578044199030088ad0507c67Test |
| رقم الانضمام: | edsdoj.9119a5d2578044199030088ad0507c67 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 15989100 22881956 25780441 |
|---|---|
| DOI: | 10.5217/ir.2023.00065 |