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NT-proBNP, C-reactive protein and soluble uPAR in a bi-ethnic male population: the SAfrEIC study.

التفاصيل البيبلوغرافية
العنوان: NT-proBNP, C-reactive protein and soluble uPAR in a bi-ethnic male population: the SAfrEIC study.
المؤلفون: Ruan Kruger, Rudolph Schutte, Hugo W Huisman, Peter Hindersson, Michael H Olsen, Jesper Eugen-Olsen, Aletta E Schutte
المصدر: PLoS ONE, Vol 8, Iss 3, p e58506 (2013)
بيانات النشر: Public Library of Science (PLoS), 2013.
سنة النشر: 2013
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: Objective and designThis cross-sectional study aimed to investigate associations between a marker of cardiac strain, the N-terminal prohormone B-type natriuretic peptide (NT-proBNP), and inflammation as reflected by either a conventional or novel inflammatory marker in a bi-ethnic South African cohort.Methods and subjectsWe measured NT-proBNP, C-reactive protein (CRP) and plasma-soluble urokinase plasminogen activator receptor (suPAR) levels along with conventional biomarkers in black (n = 117) and white (n = 116) men.ResultsNT-proBNP, CRP and suPAR levels were higher in black compared to white men. NT-proBNP was significantly associated with both CRP (r = 0.38; p = 0.001) and suPAR (r = 0.42; pConclusionThese results suggest that a low-grade inflammatory state as reflected by both a conventional and novel marker of inflammation may contribute to higher cardiovascular risk as reflected by the associations obtained with a marker of cardiac strain in black South African men.
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
العلاقة: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23516493/?tool=EBITest; https://doaj.org/toc/1932-6203Test
DOI: 10.1371/journal.pone.0058506
الوصول الحر: https://doaj.org/article/8d147cbfa05243be95459b2a683bbd7cTest
رقم الانضمام: edsdoj.8d147cbfa05243be95459b2a683bbd7c
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0058506