دورية أكاديمية
Genetically Engineered Strains: Application and Advances for 1,3-Propanediol Production from Glycerol
| العنوان: | Genetically Engineered Strains: Application and Advances for 1,3-Propanediol Production from Glycerol |
|---|---|
| المؤلفون: | Miaomiao Yang, Junhua Yun, Huanhuan Zhang, Tinashe A. Magocha, Hossain Zabed, Yanbo Xue, Ernest Fokum, Wenjing Sun, Xianghui Qi |
| المصدر: | Food Technology and Biotechnology, Vol 56, Iss 1, Pp 3-15 (2018) |
| بيانات النشر: | University of Zagreb Faculty of Food Technology and Biotechnology, 2018. |
| سنة النشر: | 2018 |
| المجموعة: | LCC:Biotechnology LCC:Food processing and manufacture |
| مصطلحات موضوعية: | glycerol, 1,3-propanediol, biosynthesis, genetically engineered strain, mutagenesis, Biotechnology, TP248.13-248.65, Food processing and manufacture, TP368-456 |
| الوصف: | 1,3-Propanediol (1,3-PD) is one of the most important chemicals widely used as monomers for synthesis of some commercially valuable products, including cosmetics, foods, lubricants and medicines. Although 1,3-PD can be synthesized both chemically and biosynthetically, the latter offers more merits over chemical approach as it is economically viable, environmentally friendly and easy to carry out. The biosynthesis of 1,3-PD can be done by transforming glycerol or other similar substrates using some bacteria, such as Clostridium butyricum and Klebsiella pneumoniae. However, these natural microorganisms pose some bottlenecks like low productivity and metabolite inhibition. To overcome these problems, recent research efforts have been focused more on the development of new strains by modifying the genome through different techniques, such as mutagenesis and genetic engineering. Genetically engineered strains obtained by various strategies cannot only gain higher yield than wild types, but also overcome some of the barriers in production by the latter. This review paper presents an overview on the recent advances in the technological approaches to develop genetically engineered microorganisms for efficient biosynthesis of 1,3-PD. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1330-9862 1334-2606 |
| العلاقة: | https://hrcak.srce.hr/file/290701Test; https://doaj.org/toc/1330-9862Test; https://doaj.org/toc/1334-2606Test |
| DOI: | 10.17113/ftb.56.01.18.5444 |
| الوصول الحر: | https://doaj.org/article/8c709b216ea34577badb201fcd3d57f4Test |
| رقم الانضمام: | edsdoj.8c709b216ea34577badb201fcd3d57f4 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 13309862 13342606 |
|---|---|
| DOI: | 10.17113/ftb.56.01.18.5444 |