التفاصيل البيبلوغرافية
العنوان:
The genomic and transcriptional landscape of primary central nervous system lymphoma
المؤلفون:
Josefine Radke , Naveed Ishaque , Randi Koll , Zuguang Gu , Elisa Schumann , Lina Sieverling , Sebastian Uhrig , Daniel Hübschmann , Umut H. Toprak , Cristina López , Xavier Pastor Hostench , Simone Borgoni , Dilafruz Juraeva , Fabienne Pritsch , Nagarajan Paramasivam , Gnana Prakash Balasubramanian , Matthias Schlesner , Shashwat Sahay , Marc Weniger , Debora Pehl , Helena Radbruch , Anja Osterloh , Agnieszka Korfel , Martin Misch , Julia Onken , Katharina Faust , Peter Vajkoczy , Dag Moskopp , Yawen Wang , Andreas Jödicke , Lorenz Trümper , Ioannis Anagnostopoulos , Dido Lenze , Ralf Küppers , Michael Hummel , Clemens A. Schmitt , Otmar D. Wiestler , Stephan Wolf , Andreas Unterberg , Roland Eils , Christel Herold-Mende , Benedikt Brors , ICGC MMML-Seq Consortium , Reiner Siebert , Stefan Wiemann , Frank L. Heppner
المصدر:
Nature Communications, Vol 13, Iss 1, Pp 1-20 (2022)
بيانات النشر:
Nature Portfolio, 2022.
سنة النشر:
2022
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Primary lymphomas of the central nervous system (PCNSL) are defined as diffuse large B-cell lymphomas (DLBCL) confined to the CNS. Here, the authors complete whole genome sequencing and RNA-seq to characterize 51 PCNSLs, and find common mutations in immune pathways and upregulated TERT expression and find distinct pathway differences between DLBCL and other primary CNS lymphomas.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-022-30050-y
الوصول الحر:
https://doaj.org/article/cd868cc84a9442afabebbc3638875fabTest
رقم الانضمام:
edsdoj.868cc84a9442afabebbc3638875fab
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