دورية أكاديمية
Application of clinico-radiologic-pathologic diagnosis of diffuse parenchymal lung diseases in children in China.
| العنوان: | Application of clinico-radiologic-pathologic diagnosis of diffuse parenchymal lung diseases in children in China. |
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| المؤلفون: | Dan Xu, Zhimin Chen, Huizhong Chen, Rongyan Huang, Shunying Zhao, Xiuyun Liu, Chunju Zhou, Yun Peng, Xinyu Yuan, Jizhen Zou, Hailing Zhang, Deyu Zhao, Enmei Liu, Yuejie Zheng, Lili Zhong, Min Lu, Jirong Lu, Guangmin Nong |
| المصدر: | PLoS ONE, Vol 10, Iss 1, p e0116930 (2015) |
| بيانات النشر: | Public Library of Science (PLoS), 2015. |
| سنة النشر: | 2015 |
| المجموعة: | LCC:Medicine LCC:Science |
| مصطلحات موضوعية: | Medicine, Science |
| الوصف: | UNLABELLED:Diffuse parenchymal lung diseases in children (chDPLD) or interstitial lung diseases in children (chILD) represent a heterogeneous group of respiratory disorders that are mostly chronic and associated with high morbidity and mortality. However, the incidence of chDPLD is so low that most pediatricians lack sufficient knowledge of chDPLD, especially in China. Based on the clinico-radiologic-pathologic (CRP) diagnosis, we tried to describe (1) the characteristics of chDPLD and (2) the ratio of each constituent of chDPLD in China. Data were evaluated, including clinical, radiographic, and pathologic results from lung biopsies. We collected 25 cases of chDPLD, 18 boys and 7 girls with a median age of 6.0 years, from 16 hospitals in China. The most common manifestations included cough (n = 24), dyspnea (n = 21), and fever (n = 4). There were three cases of exposure-related interstitial lung disease (ILD), three cases of systemic disease-associated ILD, nineteen cases of alveolar structure disorder-associated ILD, and no cases of ILD specific to infancy. Non-specific interstitial pneumonia (n = 9) was the two largest groups. CONCLUSION:Non-specific interstitial pneumonia is the main categories of chDPLD in China. Lung biopsy is always a crucial step in the final diagnosis. However, clinical and imaging studies should be carefully evaluated for their value in indicating a specific chDPLD. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1932-6203 |
| العلاقة: | http://europepmc.org/articles/PMC4287620?pdf=renderTest; https://doaj.org/toc/1932-6203Test |
| DOI: | 10.1371/journal.pone.0116930 |
| الوصول الحر: | https://doaj.org/article/865fd6e131c8433c8d7cca74a842592dTest |
| رقم الانضمام: | edsdoj.865fd6e131c8433c8d7cca74a842592d |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19326203 |
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| DOI: | 10.1371/journal.pone.0116930 |