دورية أكاديمية
Complete Hydatidiform Mole with a Coexisting Viable Male Fetus Detected by Cell-Free DNA
| العنوان: | Complete Hydatidiform Mole with a Coexisting Viable Male Fetus Detected by Cell-Free DNA |
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| المؤلفون: | Mackenzie Lemieux, Lauren Kus, Kali Stewart, Mai He, Jackson Rowe, Matthew Brady, Katherine Bligard, Megan Lawlor, Jeannie Kelly |
| المصدر: | American Journal of Perinatology Reports, Vol 13, Iss 03, Pp e49-e52 (2023) |
| بيانات النشر: | Thieme Medical Publishers, Inc., 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Gynecology and obstetrics |
| مصطلحات موضوعية: | complete hydatidiform mole, twin pregnancy, molar pregnancy, noninvasive prenatal testing, SNP-based, Gynecology and obstetrics, RG1-991 |
| الوصف: | Complete hydatidiform mole with coexisting fetus (CHMCF) is rare, and diagnosis is challenging due to limited data. Here, we present the case of a patient with noninvasive prenatal test (NIPT) resulting in “likely molar pregnancy” in the second trimester. Subsequent ultrasound confirmed a cystic appearing portion of the placenta. At 22 weeks, the patient delivered a demised fetus and two placentas. Pathology was consistent with CHMCF. This case is the first to show primary detection of a CHMCF with single-nucleotide polymorphism (SNP)-based NIPT prior to ultrasound identification. Our case suggests the use of SNP-based NIPT as an alternative noninvasive method to guide shared decision-making and clinical management for patients with this diagnosis. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2157-6998 2157-7005 |
| العلاقة: | https://doaj.org/toc/2157-6998Test; https://doaj.org/toc/2157-7005Test |
| DOI: | 10.1055/s-0043-1774727 |
| الوصول الحر: | https://doaj.org/article/856de8b79b974cd692a7381e8b4145dbTest |
| رقم الانضمام: | edsdoj.856de8b79b974cd692a7381e8b4145db |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 21576998 21577005 |
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| DOI: | 10.1055/s-0043-1774727 |