دورية أكاديمية
Barosensory vessel mechanics and the vascular sympathetic baroreflex: Impact on blood pressure homeostasis
| العنوان: | Barosensory vessel mechanics and the vascular sympathetic baroreflex: Impact on blood pressure homeostasis |
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| المؤلفون: | Guto W. Hughes, Jonathan P. Moore, Rachel N. Lord |
| المصدر: | Experimental Physiology, Vol 108, Iss 10, Pp 1245-1249 (2023) |
| بيانات النشر: | Wiley, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Physiology |
| مصطلحات موضوعية: | baroreflex, barosensory vessel unloading mechanics, healthy ageing, muscle sympathetic nerve activity, sympathetic nervous system, Physiology, QP1-981 |
| الوصف: | Abstract An age‐associated increase in arterial blood pressure is evident for apparently healthy humans. This is frequently attributed to stiffening of the central arteries and a concurrent increase in sympathetic outflow, potentially mediated by a reduced ability of the baroreceptive vessels to distend. This is supported, in part, by a reduced mechanical component of the vascular sympathetic baroreflex (i.e., a reduction in distension for a given pressure). Previous characterization of the mechanical component has assessed only carotid artery distension; however, evidence suggests that both the aortic and carotid baroreflexes are integral to blood pressure regulation. In addition, given that baroreceptors are located in the vessel wall, the change in wall tension, comprising diameter, pressure and vessel wall thickness, and the mechanics of this change might provide a better index of the baroreceptor stimulus than the previous method used to characterize the mechanical component that relies on diameter alone. This brief review summarizes the data using this new method of assessing barosensory vessel mechanics and their influence on the vascular sympathetic baroreflex across the lifespan. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1469-445X 0958-0670 |
| العلاقة: | https://doaj.org/toc/0958-0670Test; https://doaj.org/toc/1469-445XTest |
| DOI: | 10.1113/EP089686 |
| الوصول الحر: | https://doaj.org/article/8525167220f44fc9831dd0ebd82d4346Test |
| رقم الانضمام: | edsdoj.8525167220f44fc9831dd0ebd82d4346 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 1469445X 09580670 |
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| DOI: | 10.1113/EP089686 |