دورية أكاديمية
Major lower extremity amputations – risk of re-amputation, time to re-amputation, and risk factors: a nationwide cohort study from Denmark
| العنوان: | Major lower extremity amputations – risk of re-amputation, time to re-amputation, and risk factors: a nationwide cohort study from Denmark |
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| المؤلفون: | Anna Trier Heiberg Brix, Katrine Hass Rubin, Tine Nymark, Hagen Schmal, Martin Lindberg-Larsen |
| المصدر: | Acta Orthopaedica, Vol 95 (2024) |
| بيانات النشر: | Medical Journals Sweden, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Orthopedic surgery |
| مصطلحات موضوعية: | Amputation Level, Faliure, Major Lower Extremity Amputation, Prognostic factors, Re-amputation, Registry Study, Orthopedic surgery, RD701-811 |
| الوصف: | Background and purpose: Re-amputation after lower extremity amputation is frequent. The primary aim of our study was to investigate cumulative re-amputation risk after transtibial amputation (TTA), knee disarticulation (KD), and transfemoral amputation (TFA) and secondarily to investigate time to re-amputation, and risk factors. Methods: This observational cohort study was based on data from the Danish Nationwide Health registers. The population included first-time major lower extremity amputations (MLEA) performed in patients ≥ 50 years between 2010 and 2021. Both left and right sided MLEA from the same patient were included as index procedures. Results: 11,743 index MLEAs on 10,052 patients were included. The overall cumulative risks for re-amputation were 29% (95% confidence interval [CI] 27–30), 30% (CI 26–35), and 11% (CI 10–12) for TTA, KD, and TFA, respectively. 58% of re-amputations were performed within 30 days after index MLEA. Risk factors for re-amputation within 30 days were dyslipidemia (hazard ratio [HR] 1.2, CI 1.0–1.3), renal insufficiency (HR 1.2, CI 1.1–1.4), and prior vascular surgery (HR 1.3, CI 1.2–1.5). Conclusion: The risk of re-amputation was more than twice as high after TTA (29%) and KD (30%) compared with TFA (11%). Most re-amputations were conducted within 30 days of the index MLEA. Dyslipidemia, renal insufficiency, and prior vascular surgery were associated with higher risk of re-amputation. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 17453674 1745-3674 1745-3682 |
| العلاقة: | https://actaorthop.org/actao/article/view/39963Test; https://doaj.org/toc/1745-3674Test; https://doaj.org/toc/1745-3682Test |
| DOI: | 10.2340/17453674.2024.39963 |
| الوصول الحر: | https://doaj.org/article/809fbf95dedb4a44b10fff3bd4d23712Test |
| رقم الانضمام: | edsdoj.809fbf95dedb4a44b10fff3bd4d23712 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17453674 17453682 |
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| DOI: | 10.2340/17453674.2024.39963 |