دورية أكاديمية
Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer.
العنوان: | Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer. |
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المؤلفون: | Jingxiong Xu, Wei Xu, Jiyeon Choi, Yonathan Brhane, David C Christiani, Jui Kothari, James McKay, John K Field, Michael P A Davies, Geoffrey Liu, Christopher I Amos, Rayjean J Hung, Laurent Briollais |
المصدر: | PLoS Genetics, Vol 19, Iss 9, p e1010902 (2023) |
بيانات النشر: | Public Library of Science (PLoS), 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Genetics |
مصطلحات موضوعية: | Genetics, QH426-470 |
الوصف: | Common genetic variants associated with lung cancer have been well studied in the past decade. However, only 12.3% heritability has been explained by these variants. In this study, we investigate the contribution of rare variants (RVs) (minor allele frequency |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1553-7390 1553-7404 |
العلاقة: | https://doaj.org/toc/1553-7390Test; https://doaj.org/toc/1553-7404Test |
DOI: | 10.1371/journal.pgen.1010902 |
الوصول الحر: | https://doaj.org/article/7f59e12f073945058ca10e7e8ade8cdeTest |
رقم الانضمام: | edsdoj.7f59e12f073945058ca10e7e8ade8cde |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 15537390 15537404 |
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DOI: | 10.1371/journal.pgen.1010902 |