التفاصيل البيبلوغرافية
العنوان:
Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ
المؤلفون:
Lina Ding , Ying Su , Anne Fassl , Kunihiko Hinohara , Xintao Qiu , Nicholas W. Harper , Sung Jin Huh , Noga Bloushtain-Qimron , Bojana Jovanović , Muhammad Ekram , Xiaoyuan Zi , William C. Hines , Maša Alečković , Carlos Gil del Alcazar , Ryan J. Caulfield , Dennis M. Bonal , Quang-De Nguyen , Vanessa F. Merino , Sibgat Choudhury , Gabrielle Ethington , Laura Panos , Michael Grant , William Herlihy , Alfred Au , Gedge D. Rosson , Pedram Argani , Andrea L. Richardson , Deborah Dillon , D. Craig Allred , Kirsten Babski , Elizabeth Min Hui Kim , Charles H. McDonnell , Jon Wagner , Ron Rowberry , Kristie Bobolis , Celina G. Kleer , E. Shelley Hwang , Joanne L. Blum , Simona Cristea , Piotr Sicinski , Rong Fan , Henry W. Long , Saraswati Sukumar , So Yeon Park , Judy E. Garber , Mina Bissell , Jun Yao , Kornelia Polyak
المصدر:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
بيانات النشر:
Nature Portfolio, 2019.
سنة النشر:
2019
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
Myoepithelial cells prevent tumour growth and invasion in DCIS. Here, the authors show that p63 and TCF7 cooperate to regulate a transcription factor network for the maintenance of normal myoepithelial function and altered expression of these genes perturb myoepithelial function in DCIS to promote invasive progression.
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-019-12125-5
الوصول الحر:
https://doaj.org/article/784cf49197cf4d50824d3974f6c39d75Test
رقم الانضمام:
edsdoj.784cf49197cf4d50824d3974f6c39d75
قاعدة البيانات:
Directory of Open Access Journals