دورية أكاديمية
Linseed oil attenuates fatty liver disease in mice fed a high-carbohydrate diet
العنوان: | Linseed oil attenuates fatty liver disease in mice fed a high-carbohydrate diet |
---|---|
المؤلفون: | G. Godoy, C.C.O. Bernardo, L. Casagrande, M.L.M. Sérgio, J.N. Zanoni, J.V.C.M. Perles, R. Curi, R.B. Bazotte |
المصدر: | Brazilian Journal of Medical and Biological Research, Vol 56 (2023) |
بيانات النشر: | Associação Brasileira de Divulgação Científica, 2023. |
سنة النشر: | 2023 |
المجموعة: | LCC:Medicine (General) LCC:Biology (General) |
مصطلحات موضوعية: | Flaxseed oil, Omega 3 polyunsaturated fatty acids, Liver fibrosis, Hepatocellular ballooning, Hepatic steatosis, NAFLD, Medicine (General), R5-920, Biology (General), QH301-705.5 |
الوصف: | The impact of linseed oil as a lipid source on liver disease induced by a high-carbohydrate diet (HCD) was evaluated. Adult male Swiss mice received an HCD containing carbohydrates (72.1%), proteins (14.2%), and lipids (4.0%). The Control HCD group (HCD-C) received an HCD containing lard (3.6%) and soybean oil (0.4%) as lipid sources. The L10 and L100 groups received an HCD with 10 and 100% linseed oil as lipid sources, respectively. A group of mice were euthanized before receiving the diets (day 0) and the remaining groups after 56 days of receiving the diets (HCD-C, L10, and L-100 groups). Morphological and histopathological analyses, as well as collagen deposition were evaluated. Perivenous hepatocytes (PVH) of the HCD-C group were larger (P |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 1414-431X 1414-431x |
العلاقة: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2023000100664&tlng=enTest; https://doaj.org/toc/1414-431XTest |
DOI: | 10.1590/1414-431x2023e12927 |
الوصول الحر: | https://doaj.org/article/71c3864bc28b4d009d138cf75f3b6f3eTest |
رقم الانضمام: | edsdoj.71c3864bc28b4d009d138cf75f3b6f3e |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 1414431X 1414431x |
---|---|
DOI: | 10.1590/1414-431x2023e12927 |