دورية أكاديمية
Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV
العنوان: | Septin 9 induces lipid droplets growth by a phosphatidylinositol-5-phosphate and microtubule-dependent mechanism hijacked by HCV |
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المؤلفون: | Abdellah Akil, Juan Peng, Mohyeddine Omrane, Claire Gondeau, Christophe Desterke, Mickaël Marin, Hélène Tronchère, Cyntia Taveneau, Sokhavuth Sar, Philippe Briolotti, Soumaya Benjelloun, Abdelaziz Benjouad, Patrick Maurel, Valérie Thiers, Stéphane Bressanelli, Didier Samuel, Christian Bréchot, Ama Gassama-Diagne |
المصدر: | Nature Communications, Vol 7, Iss 1, Pp 1-19 (2016) |
بيانات النشر: | Nature Portfolio, 2016. |
سنة النشر: | 2016 |
المجموعة: | LCC:Science |
مصطلحات موضوعية: | Science |
الوصف: | The accumulation of lipid droplets is often observed in hepatitis C virus infection, but the mechanism of their formation is not known. Here the authors show that septin 9 expression is increased in infected livers, and a septin 9/phosphatidylinositol 5-phosphate signalling pathway regulates the growth of lipid droplets. |
نوع الوثيقة: | article |
وصف الملف: | electronic resource |
اللغة: | English |
تدمد: | 2041-1723 87126982 |
العلاقة: | https://doaj.org/toc/2041-1723Test |
DOI: | 10.1038/ncomms12203 |
الوصول الحر: | https://doaj.org/article/6bbbd7beb26d487f871269821bc6ebffTest |
رقم الانضمام: | edsdoj.6bbbd7beb26d487f871269821bc6ebff |
قاعدة البيانات: | Directory of Open Access Journals |
تدمد: | 20411723 87126982 |
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DOI: | 10.1038/ncomms12203 |