دورية أكاديمية
Yeast hydrolysate attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier damage in weaned piglets
| العنوان: | Yeast hydrolysate attenuates lipopolysaccharide-induced inflammatory responses and intestinal barrier damage in weaned piglets |
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| المؤلفون: | Runqi Fu, Chan Liang, Daiwen Chen, Gang Tian, Ping Zheng, Jun He, Jie Yu, Xiangbing Mao, Yuheng Luo, Junqiu Luo, Bing Yu |
| المصدر: | Journal of Animal Science and Biotechnology, Vol 14, Iss 1, Pp 1-15 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Animal culture LCC:Veterinary medicine |
| مصطلحات موضوعية: | Inflammatory response, Intestinal barrier, Lipopolysaccharide, Piglets, Yeast hydrolysate, Animal culture, SF1-1100, Veterinary medicine, SF600-1100 |
| الوصف: | Abstract Background Intestinal inflammation is the main risk factor causing intestinal barrier dysfunction and lipopolysaccharide (LPS) can trigger inflammatory responses in various eukaryotic species. Yeast hydrolysate (YH) possesses multi-biological effects and is received remarkable attention as a functional ingredient for improving growth performance and promoting health in animals. However, there is still inconclusive on the protective effects of dietary YH supplementation on intestinal barrier of piglets. This study was conducted to investigate the attenuate effects of YH supplementation on inflammatory responses and intestinal barrier injury in piglets challenged with LPS. Methods Twenty-four piglets (with an average body weight of 7.42 ± 0.34 kg) weaned at 21 days of age were randomly assigned to one of two dietary treatments (12 replications with one pig per pen): a basal diet or a basal diet containing YH (5 g/kg). On the 22nd d, 6 piglets in each treatment were intraperitoneally injected with LPS at 150 μg/kg BW, and the others were injected with the same amount of sterile normal saline. Four hours later, blood samples of each piglet were collected and then piglets were euthanized. Results Dietary YH supplementation increased average daily feed intake and average daily gain (P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2049-1891 |
| العلاقة: | https://doaj.org/toc/2049-1891Test |
| DOI: | 10.1186/s40104-023-00835-2 |
| الوصول الحر: | https://doaj.org/article/ac648124969c47d099fd5bfc3da33451Test |
| رقم الانضمام: | edsdoj.648124969c47d099fd5bfc3da33451 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 20491891 |
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| DOI: | 10.1186/s40104-023-00835-2 |