دورية أكاديمية

Correlating natural language processing and automated speech analysis with clinician assessment to quantify speech-language changes in mild cognitive impairment and Alzheimer’s dementia

التفاصيل البيبلوغرافية
العنوان: Correlating natural language processing and automated speech analysis with clinician assessment to quantify speech-language changes in mild cognitive impairment and Alzheimer’s dementia
المؤلفون: Anthony Yeung, Andrea Iaboni, Elizabeth Rochon, Monica Lavoie, Calvin Santiago, Maria Yancheva, Jekaterina Novikova, Mengdan Xu, Jessica Robin, Liam D. Kaufman, Fariya Mostafa
المصدر: Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-10 (2021)
بيانات النشر: BMC, 2021.
سنة النشر: 2021
المجموعة: LCC:Neurosciences. Biological psychiatry. Neuropsychiatry
LCC:Neurology. Diseases of the nervous system
مصطلحات موضوعية: Natural language processing, Automated speech analysis, Markers, Machine learning, Alzheimer’s, Dementia, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
الوصف: Abstract Background Language impairment is an important marker of neurodegenerative disorders. Despite this, there is no universal system of terminology used to describe these impairments and large inter-rater variability can exist between clinicians assessing language. The use of natural language processing (NLP) and automated speech analysis (ASA) is emerging as a novel and potentially more objective method to assess language in individuals with mild cognitive impairment (MCI) and Alzheimer’s dementia (AD). No studies have analyzed how variables extracted through NLP and ASA might also be correlated to language impairments identified by a clinician. Methods Audio recordings (n=30) from participants with AD, MCI, and controls were rated by clinicians for word-finding difficulty, incoherence, perseveration, and errors in speech. Speech recordings were also transcribed, and linguistic and acoustic variables were extracted through NLP and ASA. Correlations between clinician-rated speech characteristics and the variables were compared using Spearman’s correlation. Exploratory factor analysis was applied to find common factors between variables for each speech characteristic. Results Clinician agreement was high in three of the four speech characteristics: word-finding difficulty (ICC = 0.92, p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1758-9193
العلاقة: https://doaj.org/toc/1758-9193Test
DOI: 10.1186/s13195-021-00848-x
الوصول الحر: https://doaj.org/article/6384e3a3b5984972a0d5d4dd2b5d6b7dTest
رقم الانضمام: edsdoj.6384e3a3b5984972a0d5d4dd2b5d6b7d
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:17589193
DOI:10.1186/s13195-021-00848-x