دورية أكاديمية
Timing of surgery in patients with synchronous colorectal cancer liver metastases undergoing neoadjuvant chemotherapy: a propensity score analysis
| العنوان: | Timing of surgery in patients with synchronous colorectal cancer liver metastases undergoing neoadjuvant chemotherapy: a propensity score analysis |
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| المؤلفون: | Yaoqun Wang, Ningyuan Wen, Xianze Xiong, Jiong Lu, Bei Li, Nansheng Cheng |
| المصدر: | World Journal of Surgical Oncology, Vol 21, Iss 1, Pp 1-10 (2023) |
| بيانات النشر: | BMC, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Surgery LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | Colorectal cancer liver metastases, Hepatectomy, Neoadjuvant chemotherapy, Propensity score matching, Prognosis, Surgery, RD1-811, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Abstract Background The optimal timing of surgery after neoadjuvant chemotherapy (NAC) in patients with synchronous colorectal cancer liver metastases (SLM) remains controversial. We plan to analyze whether the choice of different surgical timings will have different effects on the perioperative and oncologic outcomes of patients. Method We retrospectively collected all patients who met the inclusion and exclusion criteria from 2010 to 2020 in West China Hospital. Patients were grouped according to time interval (TI) after NAC to surgery. The perioperative and oncologic outcomes of the two groups were compared after propensity score matching. Univariate and multivariate analyzes were used to screen factors associated with prognosis. Result Among 255 enrolled patients, 188 were matched with comparable baseline (94 each group). Patients in the 6≦TI≦8 group had longer operation time, less intraoperative blood loss, and less postoperative complications than those in the 4≦TI |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1477-7819 |
| العلاقة: | https://doaj.org/toc/1477-7819Test |
| DOI: | 10.1186/s12957-023-03162-y |
| الوصول الحر: | https://doaj.org/article/62cc43f6cff0462684c782b7c7b1bcbaTest |
| رقم الانضمام: | edsdoj.62cc43f6cff0462684c782b7c7b1bcba |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 14777819 |
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| DOI: | 10.1186/s12957-023-03162-y |