دورية أكاديمية
Thyroid dysfunction following radiofrequency ablation for benign thyroid nodules: more likely to occur within one-week and in high-risk population
| العنوان: | Thyroid dysfunction following radiofrequency ablation for benign thyroid nodules: more likely to occur within one-week and in high-risk population |
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| المؤلفون: | Nana Wang, Bowen Zheng, Tao Wu, Lei Tan, Yufan Lian, Yanping Ma, Rui Guo, Shicheng Xu, Longyi Zeng, Wen Xu, Jie Ren |
| المصدر: | International Journal of Hyperthermia, Vol 38, Iss 1, Pp 1060-1068 (2021) |
| بيانات النشر: | Taylor & Francis Group, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Medical technology |
| مصطلحات موضوعية: | radiofrequency ablation, thyroid nodule, thyroid dysfunction, thyrotoxicosis, hypothyroidism, risk factors, Medical technology, R855-855.5 |
| الوصف: | Background Radiofrequency ablation (RFA) has been recommended as the treatment for benign thyroid nodules (BTNs) by some guidelines. However, detailed follow-up instructions for thyroid function about the timing and affected populations after RFA are lacked due to insufficient researches. This 12-month prospective study aimed to evaluate the incidence and risk factors of thyroid dysfunction at different time points after RFA, especially within 1 week that previous studies didn’t concern. Methods Seventy-five euthyroid patients who underwent RFA for symptomatic BTNs were enrolled (ChiCTR-INR-16007884). The incidence of thyroid dysfunction within 1 week, at 1, 6, and 12 months after RFA was evaluated. The risk factors for different types of thyroid dysfunction in the different terms were further analyzed. Results Within 1 week after RFA, the incidence of thyroid dysfunction was as high as 36.00% unexpectedly, and only overt thyrotoxicosis and subclinical thyrotoxicosis occurred, which were significantly associated with the low-normal baseline thyrotropin (TSH) level (p = 0.001) and high ablation volume ratio (p = 0.008). From 1 to 12 months (the long term), the incidence dropped significantly and remained low (8.00–12.00%); and thyroid dysfunction presented as overt thyrotoxicosis, subclinical thyrotoxicosis, and subclinical hypothyroidism. The long-term thyrotoxicosis group had more cases with diabetes and lower baseline TSH levels. The long-term subclinical hypothyroidism group had more cases with positive thyroid peroxidase antibodies, higher baseline TSH levels, and higher ablation volume ratios. Conclusions After the RFA of BTNs, thyroid dysfunction was more likely to occur within 1 week and in populations with risk factors. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 0265-6736 1464-5157 02656736 |
| العلاقة: | https://doaj.org/toc/0265-6736Test; https://doaj.org/toc/1464-5157Test |
| DOI: | 10.1080/02656736.2021.1950849 |
| الوصول الحر: | https://doaj.org/article/62358152e57f4491b2b54c01b528cb3aTest |
| رقم الانضمام: | edsdoj.62358152e57f4491b2b54c01b528cb3a |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 02656736 14645157 |
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| DOI: | 10.1080/02656736.2021.1950849 |