دورية أكاديمية
Effects of leukoreduction on storage lesions in whole blood and blood components of dogs
| العنوان: | Effects of leukoreduction on storage lesions in whole blood and blood components of dogs |
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| المؤلفون: | Annalisa Stefani, Katia Capello, Antonio Carminato, Wendy Wurzburger, Tommaso Furlanello, Valentina Bertazzo, Elisabetta Marsilio, Elena Albertin, Giacomo La Pietra, Elisa Bozzato, Franco Mutinelli, Marta Vascellari |
| المصدر: | Journal of Veterinary Internal Medicine, Vol 35, Iss 2, Pp 936-945 (2021) |
| بيانات النشر: | Wiley, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Veterinary medicine |
| مصطلحات موضوعية: | blood, dog, leukoreduction, storage lesions, transfusion, Veterinary medicine, SF600-1100 |
| الوصف: | Abstract Background Leukoreduction is a routine procedure in human transfusion medicine but is uncommon in veterinary. Objectives To evaluate the effect of leukoreduction on the quality of canine whole blood (WB) and blood products during storage. Animals Ten canine blood donors. Methods This is a case series study. An amount of 450 mL of blood was collected from each dog. Five WB and 5 packed red blood cells (pRBC) bags were divided into 2 units each: leukoreduced (LR) and non‐leukoreduced (nLR). RBC count, erythrocytes' mean osmotic fragility (MOF), 2,3‐diphosphoglycerate (2,3‐DPG), adenosine triphosphate (ATP), percentage of hemolysis, potassium (K), lactate, glucose, and cytokines were measured weekly from day of donation (T0) to day 35 (T35); pH, coagulation times, and clotting factors were evaluated at T0 and T35 from WB and in fresh frozen plasma after 1 year of storage. Results Leukoreduction showed positive effects on lactate (T35: LR WB 14.42 mmol/L SD 2.71, nLR WB 22.42 mmol/L SD 1.86, LR pRBC 20.88 mmol/L SD 2.65, nLR pRBC 36.81 mmol/L SD 2.34; P |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1939-1676 0891-6640 |
| العلاقة: | https://doaj.org/toc/0891-6640Test; https://doaj.org/toc/1939-1676Test |
| DOI: | 10.1111/jvim.16039 |
| الوصول الحر: | https://doaj.org/article/5ea2a71d5b1449c5807c7c30cb135482Test |
| رقم الانضمام: | edsdoj.5ea2a71d5b1449c5807c7c30cb135482 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 19391676 08916640 |
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| DOI: | 10.1111/jvim.16039 |