دورية أكاديمية
Prevention and treatment of thrombosis in cancer and oncohematological patients
| العنوان: | Prevention and treatment of thrombosis in cancer and oncohematological patients |
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| المؤلفون: | O. V. Somonova, A. L. Elizarova, T. V. Davydova |
| المصدر: | Онкогематология, Vol 16, Iss 4 (2021) |
| بيانات النشر: | ABV-press, 2021. |
| سنة النشر: | 2021 |
| المجموعة: | LCC:Diseases of the blood and blood-forming organs |
| مصطلحات موضوعية: | cancer patient, thrombotic complication, low molecular weight heparin, direct oral anticoagulant, Diseases of the blood and blood-forming organs, RC633-647.5 |
| الوصف: | The purpose of the review is to highlight the current possibilities for the prevention and treatment of venous thrombotic complications in patients with cancer.The data of 52 scientific sources published in the Russian and foreign press in 1997–2020 are considered.Cancer patients are at high risk of thrombotic complications, which worsen the outcome of anticancer treatment and are one of the leading causes of death. Thrombosis in an oncological patient increases the risk of death by 30 times, which is associated with fatal thromboembolism and a more aggressive course of the disease. The leading role in the pathogenesis of thrombotic complications is played by disorders in the hemostasis system caused both by the tumor itself and by therapy. Low molecular weight heparins are considered the basis for specific prophylaxis of thromboembolic complications in cancer patients. The use of low molecular weight heparins after surgery and during chemotherapy effectively reduces the incidence of venous thrombosis. Direct oral anticoagulants are promising drugs for oral administration and are indicated as one of the treatment options for patients with tumor-associated thrombosis with a low risk of bleeding and no drug interactions with ongoing systemic chemotherapy. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | Russian |
| تدمد: | 1818-8346 2413-4023 |
| العلاقة: | https://oncohematology.abvpress.ru/ongm/article/view/503Test; https://doaj.org/toc/1818-8346Test; https://doaj.org/toc/2413-4023Test |
| DOI: | 10.17650/1818-8346-2021-16-4-40-49 |
| الوصول الحر: | https://doaj.org/article/5ab919f5a07542d78378efdf409cba86Test |
| رقم الانضمام: | edsdoj.5ab919f5a07542d78378efdf409cba86 |
| قاعدة البيانات: | Directory of Open Access Journals |
| تدمد: | 18188346 24134023 |
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| DOI: | 10.17650/1818-8346-2021-16-4-40-49 |