التفاصيل البيبلوغرافية
العنوان:
Molecular and clinical determinants of response and resistance to rucaparib for recurrent ovarian cancer treatment in ARIEL2 (Parts 1 and 2)
المؤلفون:
Elizabeth M. Swisher , Tanya T. Kwan , Amit M. Oza , Anna V. Tinker , Isabelle Ray-Coquard , Ana Oaknin , Robert L. Coleman , Carol Aghajanian , Gottfried E. Konecny , David M. O’Malley , Alexandra Leary , Diane Provencher , Stephen Welch , Lee-may Chen , Andrea E. Wahner Hendrickson , Ling Ma , Prafull Ghatage , Rebecca S. Kristeleit , Oliver Dorigo , Ashan Musafer , Scott H. Kaufmann , Julia A. Elvin , Douglas I. Lin , Setsuko K. Chambers , Erin Dominy , Lan-Thanh Vo , Sandra Goble , Lara Maloney , Heidi Giordano , Thomas Harding , Alexander Dobrovic , Clare L. Scott , Kevin K. Lin , Iain A. McNeish
المصدر:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
بيانات النشر:
Nature Portfolio, 2021.
سنة النشر:
2021
المجموعة:
LCC:Science
مصطلحات موضوعية:
Science
الوصف:
The identification of biomarkers of response to PARP inhibitors can enable selection of appropriate ovarian cancer patients for treatment. In this study, the authors report clinical results and exploratory biomarker analyses from the ARIEL2 phase 2 clinical trial on the safety and efficacy of the PARP inhibitor rucaparib in patients with recurrent ovarian cancers
نوع الوثيقة:
article
وصف الملف:
electronic resource
اللغة:
English
تدمد:
2041-1723
العلاقة:
https://doaj.org/toc/2041-1723Test
DOI:
10.1038/s41467-021-22582-6
الوصول الحر:
https://doaj.org/article/4c0bb318d2464bacb5fcd01f6ceefda3Test
رقم الانضمام:
edsdoj.4c0bb318d2464bacb5fcd01f6ceefda3
قاعدة البيانات:
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