دورية أكاديمية
RNF128 expression in lung adenocarcinoma is a favorable prognostic factor associated with decreased tumor‐associated macrophages
| العنوان: | RNF128 expression in lung adenocarcinoma is a favorable prognostic factor associated with decreased tumor‐associated macrophages |
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| المؤلفون: | Syuusuke Fujimoto, Kadota Kyuichi, Yamada Kaede, Yoshida Chihiro, Ibuki Emi, Ishikawa Ryo, Haba Reiji, Yajima Toshiki, Hiroyasu Yokomise |
| المصدر: | Thoracic Cancer, Vol 14, Iss 17, Pp 1581-1588 (2023) |
| بيانات النشر: | Wiley, 2023. |
| سنة النشر: | 2023 |
| المجموعة: | LCC:Neoplasms. Tumors. Oncology. Including cancer and carcinogens |
| مصطلحات موضوعية: | carcinogenesis, immunotherapy, lung adenocarcinoma, tumor‐associated macrophages, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282 |
| الوصف: | Abstract Objectives Molecular‐level research has linked RING finger (RNF) protein family members to carcinogenesis and tumor progression. Among them, RNF128 is related to tumor progression, but reports on its association with lung cancer are few. This study aimed to clarify the unknown association between RNF128 expression and clinical outcomes in patients with lung adenocarcinoma. Methods Clinical data of 545 patients with therapy‐naïve lung adenocarcinoma who underwent lobectomy with systematic lymph node dissection between 1999 and 2016 were retrospectively reviewed. Histological and immunohistochemical analyses were conducted to evaluate the relationship between RNF128 expression and prognosis. Results Among adenocarcinoma histologic types, acinar, micropapillary, and solid tumors did not express RNF128 compared with other histologic types (p |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 1759-7714 1759-7706 |
| العلاقة: | https://doaj.org/toc/1759-7706Test; https://doaj.org/toc/1759-7714Test |
| DOI: | 10.1111/1759-7714.14901 |
| الوصول الحر: | https://doaj.org/article/d493f7303a8247f2a9c75913ba2bb853Test |
| رقم الانضمام: | edsdoj.493f7303a8247f2a9c75913ba2bb853 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 17597714 17597706 |
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| DOI: | 10.1111/1759-7714.14901 |