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Development and validation of a predictive model of in-hospital mortality in COVID-19 patients.

التفاصيل البيبلوغرافية
العنوان: Development and validation of a predictive model of in-hospital mortality in COVID-19 patients.
المؤلفون: Diego Velasco-Rodríguez, Juan-Manuel Alonso-Dominguez, Rosa Vidal Laso, Daniel Lainez-González, Aránzazu García-Raso, Sara Martín-Herrero, Antonio Herrero, Inés Martínez Alfonzo, Juana Serrano-López, Elena Jiménez-Barral, Sara Nistal, Manuel Pérez Márquez, Elham Askari, Jorge Castillo Álvarez, Antonio Núñez, Ángel Jiménez Rodríguez, Sarah Heili-Frades, César Pérez-Calvo, Miguel Górgolas, Raquel Barba, Pilar Llamas-Sillero
المصدر: PLoS ONE, Vol 16, Iss 3, p e0247676 (2021)
بيانات النشر: Public Library of Science (PLoS), 2021.
سنة النشر: 2021
المجموعة: LCC:Medicine
LCC:Science
مصطلحات موضوعية: Medicine, Science
الوصف: We retrospectively evaluated 2879 hospitalized COVID-19 patients from four hospitals to evaluate the ability of demographic data, medical history, and on-admission laboratory parameters to predict in-hospital mortality. Association of previously published risk factors (age, gender, arterial hypertension, diabetes mellitus, smoking habit, obesity, renal failure, cardiovascular/ pulmonary diseases, serum ferritin, lymphocyte count, APTT, PT, fibrinogen, D-dimer, and platelet count) with death was tested by a multivariate logistic regression, and a predictive model was created, with further validation in an independent sample. A total of 2070 hospitalized COVID-19 patients were finally included in the multivariable analysis. Age 61-70 years (p80 years (p2 ULN (p = 0.003; OR: 1.79; 95%CI: 1.22 to 2.62), and prolonged PT (p
نوع الوثيقة: article
وصف الملف: electronic resource
اللغة: English
تدمد: 1932-6203
العلاقة: https://doaj.org/toc/1932-6203Test
DOI: 10.1371/journal.pone.0247676
الوصول الحر: https://doaj.org/article/c446bdcb696e418bb90f1a02d80fff41Test
رقم الانضمام: edsdoj.446bdcb696e418bb90f1a02d80fff41
قاعدة البيانات: Directory of Open Access Journals
الوصف
تدمد:19326203
DOI:10.1371/journal.pone.0247676