دورية أكاديمية
A Case of Acute Disseminated Encephalomyelitis in Adults: Unravelling the Influenza B and Leptospirosis Co-infection
| العنوان: | A Case of Acute Disseminated Encephalomyelitis in Adults: Unravelling the Influenza B and Leptospirosis Co-infection |
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| المؤلفون: | Govind Shiddapur, Sai Mounika Adapa, Kalyan Kumar Reddy Vutukuru, Mohith Prakash Kondapalli, Sonali Agarwal |
| المصدر: | Journal of Clinical and Diagnostic Research, Vol 18, Iss 06, Pp 07-10 (2024) |
| بيانات النشر: | JCDR Research and Publications Private Limited, 2024. |
| سنة النشر: | 2024 |
| المجموعة: | LCC:Medicine |
| مصطلحات موضوعية: | immunisation, infection, neurological, quadriparesis, steroids, Medicine |
| الوصف: | Acute Disseminated Encephalomyelitis (ADEM) is a neurological disorder characterised by demyelination, where the immune system targets the Central Nervous System (CNS). This condition typically develops rapidly, with neurological symptoms appearing within days to weeks following viral infections or immunisations. Before the onset of neurological manifestations, patients often experience systemic symptoms such as fever, headache, malaise, and myalgias. The transition from the febrile phase of illness to neurological symptoms generally occurs with a latency period of 7 to 14 days. ADEM is commonly referred to as “post-infectious,” “para-infectious,” “post-exanthematous,” or “post-vaccinal” encephalomyelitis. Recognised as a potential cause of permanent neurological disability, ADEM frequently affects individuals early in life, underscoring the significance of understanding this disease entity, particularly in the context of routine immunisation practices. Herein, the authors present the case of a 28-year-old female, who presented with quadriparesis in a drowsy state following a febrile illness. Upon further evaluation, she was diagnosed with a co-infection of Influenza B and leptospirosis, confirmed by positive serological tests. Magnetic Resonance Imaging (MRI) of the brain revealed hyperintensities suggestive of ADEM in multiple areas of the brainstem and thalamus, while Cerebrospinal Fluid (CSF) examination showed an albumin-cytological dissociative picture, further supporting the diagnosis. Treatment comprised a pulse steroid regimen followed by oral steroid tapering. Subsequently, the patient demonstrated clinical improvement over the course of a week, with progressive enhancements observed during follow-up assessments. The present case highlights the importance of prompt recognition and management of ADEM, emphasising the role of corticosteroid therapy in achieving favourable patient outcomes. |
| نوع الوثيقة: | article |
| وصف الملف: | electronic resource |
| اللغة: | English |
| تدمد: | 2249-782X 0973-709X |
| العلاقة: | https://www.jcdr.net/articles/PDF/19497/70148_CETest[Ra1]_F(SS)_QC(AN_RDW_IS)_PF1(RI_DK_OM)_PfA_NC(KM)_PN(KM).pdf; https://doaj.org/toc/2249-782XTest; https://doaj.org/toc/0973-709XTest |
| DOI: | 10.7860/JCDR/2024/70148.19497 |
| الوصول الحر: | https://doaj.org/article/440349ba7b374bacbf8afddd28e6f963Test |
| رقم الانضمام: | edsdoj.440349ba7b374bacbf8afddd28e6f963 |
| قاعدة البيانات: | Directory of Open Access Journals |
Full Text Finder | تدمد: | 2249782X 0973709X |
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| DOI: | 10.7860/JCDR/2024/70148.19497 |